Anticarcinogenecity of microbiota and probiotics in breast cancer

SS Malik, A Saeed, M Baig, N Asif… - … journal of food …, 2018 - Taylor & Francis
Breast cancer is one of the most important causes of cancer related morbidity and mortality
in the world. Along with genetic, environmental factors also play a multifaceted role in the …

Insights into the mechanisms driven by H3K4 KMTs in pancreatic cancer

KC LaRue-Nolan, GL Raja Arul, AN Sigafoos… - Biochemical …, 2024 - portlandpress.com
Pancreatic cancer is a malignancy arising from the endocrine or exocrine compartment of
this organ. Tumors from exocrine origin comprise over 90% of all pancreatic cancers …

Risk factors for prostate cancer: A multifactorial case-control study

SS Malik, R Batool, N Masood, A Yasmin - Current problems in cancer, 2018 - Elsevier
Prostate cancer is the third most commonly diagnosed cancer among Pakistani men. It is a
multifactorial disease involving genetics together with environmental factors. Countries …

Genetic polymorphism of GSTM1 and GSTT1 and risk of prostatic carcinoma-a meta-analysis of 7,281 prostate cancer cases and 9,082 healthy controls

SS Malik, Z Kazmi, I Fatima, R Shabbir… - Asian Pacific Journal …, 2016 - journal.waocp.org
Genetic polymorphisms constitute one of the reasons behind the racial variation in prostate
cancer occurrence. Published studies regarding genetic associations of glutathione S …

Downregulation of GSTM2 enhances gemcitabine chemosensitivity of pancreatic cancer in vitro and in vivo

L Peng, L Zhuang, K Lin, Y Yao, Y Zhang, T Arumugam… - Pancreatology, 2021 - Elsevier
Abstract Glutathione-S-transferases (GSTs) not only show cytoprotective role and their
involvement in the development of anticancer drug resistance, but also transmit signals that …

Transcriptional regulation by the KMT2 histone H3K4 methyltransferases

K Park, JA Kim, J Kim - Biochimica et Biophysica Acta (BBA)-Gene …, 2020 - Elsevier
Abstract Histone lysine methyltransferase 2 (KMT2) proteins form multimeric enzymatic
complexes that methylate lysine 4 on histone H3 (H3K4) at transcription regulatory elements …

An insight into clinical outcome of XPG polymorphisms in breast cancer

SS Malik, S Mubarik, N Masood, MT Khadim - Molecular biology reports, 2018 - Springer
XPG polymorphisms are associated with varied clinical outcomes in different cancers but up-
till now no study has been reported on breast cancer. Therefore, current study was aimed to …

Effect of redox‐responsive DTSSP crosslinking on poly(l‐lysine)‐grafted‐poly(ethylene glycol) nanoparticles for delivery of proteins

J Seaberg, N Flynn, A Cai… - Biotechnology and …, 2020 - Wiley Online Library
Therapeutic proteins are utilized in a variety of clinical applications, but side effects and
rapid in vivo clearance still present hurdles. An approach that addresses both drawbacks is …

[HTML][HTML] Genetic polymorphism in ERCC5 and breast cancer risk

SS Malik, S Mubarik, M Baig, N Masood… - Molecular Biology …, 2019 - ncbi.nlm.nih.gov
ERCC5 plays crucial role in excision repair DNA damage induced by UV in NER pathway.
Single neuleotide polymorphism in ERCC5 were responsible for different cancers …

[HTML][HTML] KRAS and BRAF genetic alterations in lung cancer: A case− control study

HA Sawal, SI Shah, SS Malik, S Mehmood… - Journal of Cancer …, 2024 - journals.lww.com
Aim: To analyze the mutations of KRAS and BRAF in LC patients among Pakistani
population. Settings and Design: The study has been carried out at universities and health …