As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …

The Natural Cytotoxicity Receptors (NCRs), NKp46, NKp44, and NKp30, were some of the
first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted …

Over the last decade, various new therapies have been developed to promote anti-tumor
immunity. Despite interesting clinical results in hematological malignancies, the …

Natural killer (NK) cells were originally defined as effector lymphocytes of innate immunity
endowed with constitutive cytolytic functions. More recently, a more nuanced view of NK …

Natural killer (NK) cells are part of the innate immune defense against infection and cancer
and are especially useful in combating certain viral pathogens. The utility of NK cells in …

Overproduction of cytokines by T helper 2 (Th2) cells in the lung is thought to be a cause of
asthma. Here we report that innate lymphocytes termed lung natural helper (LNH) cells are a …

Systems approaches have been used to describe molecular signatures driving immunity to
influenza vaccination in humans. Whether such signatures are similar across multiple …

NK cell cytotoxicity is controlled by numerous NK inhibitory and activating receptors. Most of
the inhibitory receptors bind MHC class I proteins and are expressed in a variegated …

Natural killer (NK) cells are innate lymphoid cells, and their presence within human tumors
correlates with better prognosis. However, the mechanisms by which NK cells control tumors …

Innate lymphoid cells (ILCs) are immune cells that lack a specific antigen receptor yet can
produce an array of effector cytokines that in variety match that of T helper cell subsets. ILCs …