Peptides: Production, bioactivity, functionality, and applications

M Hajfathalian, S Ghelichi… - Critical reviews in …, 2018 - Taylor & Francis
Production of peptides with various effects from proteins of different sources continues to
receive academic attention. Researchers of different disciplines are putting increasing efforts …

Potential therapeutic applications of multifunctional host-defense peptides from frog skin as anti-cancer, anti-viral, immunomodulatory, and anti-diabetic agents

JM Conlon, M Mechkarska, ML Lukic, PR Flatt - Peptides, 2014 - Elsevier
Frog skin constitutes a rich source of peptides with a wide range of biological properties.
These include host-defense peptides with cytotoxic activities against bacteria, fungi …

[HTML][HTML] Anticancer potential of bioactive peptides from animal sources

L Wang, C Dong, X Li, W Han, X Su - Oncology reports, 2017 - spandidos-publications.com
Cancer is the most common cause of human death worldwide. Conventional anticancer
therapies, including chemotherapy and radiation, are associated with severe side effects …

Antimicrobial peptides as novel therapeutics for non-small cell lung cancer

NK Kunda - Drug discovery today, 2020 - Elsevier
Highlights•AMPs can selectively target and destroy cancer cells but not healthy cells.•AMPs
exhibit minimal systemic toxicity and minimal chance for acquiring resistance.•NSCLC cells …

[HTML][HTML] Marine peptides in breast cancer: Therapeutic and mechanistic understanding

S Ahmed, H Mirzaei, M Aschner, A Khan… - Biomedicine & …, 2021 - Elsevier
Breast cancer is the most prevalent invasive form of cancer in females and posing a great
challenge for overcoming disease burden. The growth in global cancer deaths mandates the …

[HTML][HTML] Host-defense peptides with therapeutic potential from skin secretions of frogs from the family pipidae

JM Conlon, M Mechkarska - Pharmaceuticals, 2014 - mdpi.com
Skin secretions from frogs belonging to the genera Xenopus, Silurana, Hymenochirus, and
Pseudhymenochirus in the family Pipidae are a rich source of host-defense peptides with …

Functions of antimicrobial peptides in vertebrates

E Edilia Avila - Current Protein and Peptide Science, 2017 - ingentaconnect.com
Objective: The aim of this review is to examine the multiple activities of antimicrobial
peptides (AMPs) in vertebrates. Content: The largest AMP families are the cathelicidins and …

[HTML][HTML] The role of peptides in reversing chemoresistance of breast cancer: current facts and future prospects

Y Huang, H Peng, A Zeng, L Song - Frontiers in Pharmacology, 2023 - frontiersin.org
Breast cancer is the first malignant tumor in women, and its incidence is also increasing year
by year. Chemotherapy is one of the standard therapies for breast cancer, but the resistance …

Peptides from frog skin with potential for development into agents for Type 2 diabetes therapy

JM Conlon, M Mechkarska, YH Abdel-Wahab, PR Flatt - Peptides, 2018 - Elsevier
Several frog skin peptides, first identified as result of their antimicrobial or
immunomodulatory activities, have subsequently been shown to stimulate insulin release …

[HTML][HTML] Purification, Conformational Analysis and Cytotoxic Activities of Host-Defense Peptides from the Giant Gladiator Treefrog Boana boans (Hylidae: Hylinae)

JM Conlon, L Guilhaudis, S Attoub, L Coquet… - Antibiotics, 2023 - mdpi.com
Frogs from the extensive amphibian family Hylidae are a rich source of peptides with
therapeutic potential. Peptidomic analysis of norepinephrine-stimulated skin secretions from …