echocardiogram) may be expected to facilitate the identification of patients with chest pain of
an ischemic etiology (angina). In a patient presenting to the emergency department with …

Family history is an important independent risk factor for coronary artery disease (CAD), and
identification of susceptibility genes for this common, complex disease is a vital goal …

Ath1 is a quantitative trait locus on mouse chromosome 1 that renders C57BL/6 mice
susceptible and C3H/He mice resistant to diet-induced atherosclerosis. The quantitative trait …

Objective To examine the role of the variants of the PTPN22 and HLA–DRB1 genes as
predictors of mortality in inflammatory polyarthritis (IP) and rheumatoid arthritis (RA) …

Atherosclerotic cardiovascular disease (CVD) is a major health problem in the United States
and around the world. Evidence accumulated over decades convincingly demonstrates that …

Genetic studies provide new insights into the pathogenesis of coronary artery disease and
myocardial infarction. Future studies will focus on identification of new disease-causing …

Cardiovascular disease is a leading cause of mortality in the United States, and is a
significant cause of death worldwide. In 2002, it accounted for 38.0% of all deaths in the US …

The ability to predict a patient's drug response on the basis of their genetic information is
expected to decrease attrition during the development of new, innovative drugs, and reduce …

Atherosclerotic involvement in the coronary arteries, which can result in heart attack and
sudden death, is a common disease and prototypic of a complex human trait. To understand …

Mutations in MEF2A have been implicated in an autosomal dominant form of coronary artery
disease (adCAD1). In this study we sought to determine whether severe mutations in MEF2A …