Arginine (L-arginine), is an amino acid involved in a number of biological processes,
including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide …

An important factor in the transition from an open to a closed circulatory system was a
change in vessel wall structure and composition that enabled the large arteries to store and …

Arginine has multiple metabolic fates and thus is one of the most versatile amino acids. Not
only is it metabolically interconvertible with the amino acids proline and glutamate, but it also …

ARGINASE: A CRITICAL REGULATOR OF NITRIC OXIDE SYNTHESIS AND VASCULAR
FUNCTION - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Mechanical loads induce changes in the structure, composition, and function of living
tissues. Cells in tissues are responsible for these changes, which cause physiological or …

As arginine can serve as precursor to a wide range of compounds, including nitric oxide,
creatine, urea, polyamines, proline, glutamate and agmatine, there is considerable interest …

Arginase, a binuclear manganese metalloenzyme in the urea, catalyzes the hydrolysis of L-
arginine to urea and L-ornithine. Both isoforms, arginase 1 and arginase 2 perform …

While transport processes for amino acids and glucose have long been known to be
expressed in the luminal and abluminal membranes of the endothelium comprising the …

This review summarizes the current literature and the open questions regarding the
physiology and pathophysiology of the mechanical effects of heart rate on the vessel wall …

The vascular smooth muscle cell (VSMC) is surrounded by a complex extracellular matrix
that provides and modulates a variety of biochemical and mechanical cues that guide cell …