[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics
A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …
Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion
W Tian, N Lei, J Zhou, M Chen, R Guo, B Qin, Y Li… - Cell Death & …, 2022 - nature.com
Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …
Exosomal miRNA-mediated intercellular communications and immunomodulatory effects in tumor microenvironments
Extracellular communication, in other words, crosstalk between cells, has a pivotal role in
the survival of an organism. This communication occurs by different methods, one of which is …
the survival of an organism. This communication occurs by different methods, one of which is …
Biomembrane-based nanostructures for cancer targeting and therapy: from synthetic liposomes to natural biomembranes and membrane-vesicles
The translational success of liposomes in chemotherapeutics has already demonstrated the
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …
JAK/STAT signaling: molecular targets, therapeutic opportunities, and limitations of targeted inhibitions in solid malignancies
JAK/STAT signaling pathway is one of the important regulatory signaling cascades for the
myriad of cellular processes initiated by various types of ligands such as growth factors …
myriad of cellular processes initiated by various types of ligands such as growth factors …
The role of extracellular vesicles in the hallmarks of cancer and drug resistance
Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …
Exosomal miRNAs in tumor microenvironment
S Tan, L Xia, P Yi, Y Han, L Tang, Q Pan, Y Tian… - Journal of Experimental …, 2020 - Springer
Tumor microenvironment (TME) is the internal environment in which tumor cells survive,
consisting of tumor cells, fibroblasts, endothelial cells, and immune cells, as well as non …
consisting of tumor cells, fibroblasts, endothelial cells, and immune cells, as well as non …
Exosomes as biomarkers for female reproductive diseases diagnosis and therapy
Cell–cell communication is an essential mechanism for the maintenance and development
of various organs, including the female reproductive system. Today, it is well-known that the …
of various organs, including the female reproductive system. Today, it is well-known that the …
Monocytes educated by cancer-associated fibroblasts secrete exosomal miR-181a to activate AKT signaling in breast cancer cells
K Pakravan, M Mossahebi-Mohammadi… - Journal of Translational …, 2022 - Springer
Abstract Background Cancer-associated fibroblasts (CAFs), one of the major components of
the tumor stroma, contribute to an immunosuppressive tumor microenvironment (TME) …
the tumor stroma, contribute to an immunosuppressive tumor microenvironment (TME) …
Pioneer role of extracellular vesicles as modulators of cancer initiation in progression, drug therapy, and vaccine prospects
Cancer is one of the leading diseases, causing deaths worldwide. Nearly 10 million deaths
were reported in 2020 due to cancer alone. Several factors are involved in cancer …
were reported in 2020 due to cancer alone. Several factors are involved in cancer …