Chirality is a key factor in the safety and efficacy of many drug products and thus the
production of single enantiomers of drug intermediates has become increasingly important …

Nucleoside phosphorylases (NPs) are transferases that catalyse the reversible cleavage of
the glycosidic bond of ribo-or deoxyribo nucleosides, in the presence of inorganic …

Nucleosides primarily consist of a nitrogenous base (nucleobase), which is either a purine
base or a pyrimidine base and a five-carbon sugar (pentose). The base and sugar are …

Purine nucleoside phosphorylase (PNP) catalyzes the synthesis and phosphorolysis of
purine nucleosides, interconverting nucleosides with their corresponding purine base and …

Bacillus coagulans CECT 12, Bacillus psychrosaccharolyticus CECT 4074, Lactobacillus sp.
CECT 4219 and Psychrobacter immobilis CECT 4492 have been characterised, after a …

Different supports, such as alginate, agar, agarose, and polyacrylamide, were used to
immobilize Escherichia coli BL 21 by entrapment techniques. The transglycosylation …

Biocatalysed synthesis of nucleosides was carried out using immobilised whole cells of
Escherichia coli ATCC 47092, Enterobacter gergoviae CECT 857 and Citrobacter …

Nucleosides constitute an extensive group of natural and chemically modified compounds
that display a wide range of structures and activities. Different biocatalysts have been …

Biocatalysed purine nucleoside synthesis was carried out using immobilised Enterobacter
gergoviae CECT 875. Similar yields (80–95%) in adenosine were obtained with both free …

2, 6-Diaminopurine nucleosides are used as pharmaceutical drugs or prodrugs against
cancer and viral diseases. The synthesis of 2, 6-diaminopurine riboside,-2′-deoxyriboside …