Elastin and collagen fibre microstructure of the human aorta in ageing and disease: a review

A Tsamis, JT Krawiec, DA Vorp - Journal of the royal …, 2013 - royalsocietypublishing.org
Aortic disease is a significant cause of death in developed countries. The most common
forms of aortic disease are aneurysm, dissection, atherosclerotic occlusion and ageing …

Constitutive interpretation of arterial stiffness in clinical studies: a methodological review

KD Reesink, B Spronck - American Journal of Physiology …, 2019 - journals.physiology.org
Clinical assessment of arterial stiffness relies on noninvasive measurements of regional
pulse wave velocity or local distensibility. However, arterial stiffness measures do not …

A database of virtual healthy subjects to assess the accuracy of foot-to-foot pulse wave velocities for estimation of aortic stiffness

M Willemet, P Chowienczyk… - American Journal of …, 2015 - journals.physiology.org
While central (carotid-femoral) foot-to-foot pulse wave velocity (PWV) is considered to be the
gold standard for the estimation of aortic arterial stiffness, peripheral foot-to-foot PWV …

Aging is associated with changes to the biomechanical properties of the posterior cerebral artery and parenchymal arterioles

JM Diaz-Otero, H Garver, GD Fink… - American Journal …, 2016 - journals.physiology.org
Artery remodeling, described as a change in artery structure, may be responsible for the
increased risk of cardiovascular disease with aging. Although the risk for stroke is known to …

Characterization of biaxial mechanical behavior of porcine aorta under gradual elastin degradation

S Zeinali-Davarani, MJ Chow, R Turcotte… - Annals of biomedical …, 2013 - Springer
Arteries are composed of multiple constituents that endow the wall with proper structure and
function. Many vascular diseases are associated with prominent mechanical and biological …

Fiber micro-architecture in the longitudinal-radial and circumferential-radial planes of ascending thoracic aortic aneurysm media

A Tsamis, JA Phillippi, RG Koch, S Pasta… - Journal of …, 2013 - Elsevier
It was recently demonstrated by our group that the delamination strength of ascending
thoracic aortic aneurysms (ATAA) was lower than that of control (CTRL, non-aneurysmal) …

A custom image-based analysis tool for quantifying elastin and collagen micro-architecture in the wall of the human aorta from multi-photon microscopy

RG Koch, A Tsamis, A D'Amore, WR Wagner… - Journal of …, 2014 - Elsevier
The aorta possesses a micro-architecture that imparts and supports a high degree of
compliance and mechanical strength. Alteration of the quantity and/or arrangement of the …

[HTML][HTML] Extracellular matrix fiber microarchitecture is region-specific in bicuspid aortic valve-associated ascending aortopathy

A Tsamis, JA Phillippi, RG Koch, PG Chan… - The Journal of thoracic …, 2016 - Elsevier
Objective Ascending thoracic aortic aneurysm (ATAA) in patients with bicuspid aortic valve
(BAV) commonly dilate asymmetrically compared with patients with tricuspid aortic valve …

Modeling lamellar disruption within the aortic wall using a particle-based approach

H Ahmadzadeh, MK Rausch, JD Humphrey - Scientific reports, 2019 - nature.com
Aortic dissections associate with medial degeneration, thus suggesting a need to
understand better the biophysical interactions between the cells and matrix that constitute …

Non-destructive 3D characterization of the blood vessel wall microstructure in different species and blood vessel types using contrast-enhanced microCT and …

L Leyssens, T Balcaen, M Pétré, NB Ayllón… - Acta Biomaterialia, 2023 - Elsevier
To improve the current treatment for vascular diseases, such as vascular grafts, intravascular
stents, and balloon angioplasty intervention, the evaluation of the native blood vessel …