Purpose Reactive hyperemia (RH) is widely used for the investigation of macrovascular
(flow-mediated dilation, or FMD) and microvascular (near-infrared spectroscopy-vascular …

This study aimed to elucidate the effects of change in estrogen during the menstrual cycle
and menopause on shear-mediated dilation of the internal carotid artery (ICA), a potential …

Men and women exhibit different near-infrared spectroscopy (NIRS) outcomes in response
to vascular occlusion tests (VOT), which may be due to phenotypic characteristics or different …

The onset of menopause and accompanying changes to ovarian hormones often precedes
endothelial dysfunction in women. In particular, accelerated impairments in macrovascular …

Blood flow changes in response to exercise have been attributed, among other factors, to
the effect of vasodilators factors on the microvasculature, suggesting a close relationship …

New Findings What is the central question of this study? What are the effects of the
menstrual (early follicular and mid‐luteal) or monophasic oral contraceptive (inactive‐and …

Near-infrared spectroscopy combined with vascular occlusion test (NIRS-VOT) is a reactive
hyperemia technique for in vivo evaluation of skeletal muscle microvascular reactivity …

The near-infrared spectroscopy (NIRS) vascular occlusion test (VOT) assesses
microvascular reperfusion. Two strategies have been used to quantify reperfusion following …

Endothelial dysfunction is associated with cardiovascular disease development, nitric oxide
(NO) deficiencies, and may be limb or sex-specific. Prior in vitro work indicated that the …

Research involving human subjects in ambulatory settings is a critical link in the chain
comprising translational research, spanning preclinical research to human subject and …