Emerging role of microRNA-21 in cancer
YH Feng, CJ Tsao - Biomedical reports, 2016 - spandidos-publications.com
MicroRNAs (miRs) are a class of single-stranded RNA molecules of 15-27 nucleotides in
length that regulate gene expression at the post-translational level. miR-21 is one of the …
length that regulate gene expression at the post-translational level. miR-21 is one of the …
Linking cell mechanical memory and cancer metastasis
E Cambria, MF Coughlin, MA Floryan… - Nature Reviews …, 2024 - nature.com
Metastasis causes most cancer-related deaths; however, the efficacy of anti-metastatic drugs
is limited by incomplete understanding of the biological mechanisms that drive metastasis …
is limited by incomplete understanding of the biological mechanisms that drive metastasis …
Integrated genomic characterization of papillary thyroid carcinoma
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
Early studies have shown how aberrantly expressed microRNAs are a hallmark of several
diseases like cancer. MicroRNA expression profiling was shown to be associated with …
diseases like cancer. MicroRNA expression profiling was shown to be associated with …
[HTML][HTML] Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy
Q Zhan, K Yi, H Qi, S Li, X Li, Q Wang, Y Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Developing an effective nanoplatform to realize'multi-in-one'is essential to
broaden the therapeutic potential of combination therapy. Exosomes are ideal candidates …
broaden the therapeutic potential of combination therapy. Exosomes are ideal candidates …
Progress in microRNA delivery
Y Zhang, Z Wang, RA Gemeinhart - Journal of controlled release, 2013 - Elsevier
MicroRNAs (miRNAs) are non-coding endogenous RNAs that direct post-transcriptional
regulation of gene expression by several mechanisms. Activity is primarily through binding …
regulation of gene expression by several mechanisms. Activity is primarily through binding …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
Integrating mechanisms of pulmonary fibrosis
TA Wynn - Journal of Experimental Medicine, 2011 - rupress.org
Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …
The role of microRNA-21 (miR-21) in pathogenesis, diagnosis, and prognosis of gastrointestinal cancers: A review
MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of several
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
MicroRNAs in development and disease
D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …