The mammalian retina provides an excellent opportunity to study glia–neuron interactions
and the interactions of glia with blood vessels. Three main types of glial cells are found in …

Rapid progress has been made in the understanding of the molecular interactions that result
in cell adhesion. Many adhesive proteins present in extracellular matrices and in the blood …

Neuronal growth cones navigate over long distances along specific pathways to find their
correct targets. The mechanisms and molecules that direct this pathfinding are the topics of …

An astonishing number of extracellular matrix glycoproteins are expressed in dynamic
patterns in the developing and adult nervous system. Neural stem cells, neurons, and glia …

Retinal organoids are three-dimensional structures derived from human pluripotent stem
cells (hPSCs) which recapitulate the spatial and temporal differentiation of the retina, serving …

The functioning of the nervous system depends upon the underlying detailed and highly
stereotyped patterns of neuronal connectivity. How these precise patterns of synaptic …

Collagen type IV, laminin, heparan sulfate proteoglycans, nidogen (entactin) and BM‐40
(osteonectin, SPARC) represent major structural proteins of basement membranes. They are …

CNS white matter from higher vertebrates and cultured differentiated oligodendrocytes are
nonpermissive substrates for neurite growth and fibroblast spreading. Membrane proteins of …

In the developing nervous system, axons project considerable distances along stereotyped
pathways to reach their targets. Axon guidance depends partly on the recognition of cell …

The development of neurons and virtually all other cell types in the organism depends upon
interactions with molecules in their environment. Studics of individual cell types have …