Autophagy and inflammation in chronic respiratory disease
AC Racanelli, SA Kikkers, AMK Choi, SM Cloonan - Autophagy, 2018 - Taylor & Francis
Persistent inflammation within the respiratory tract underlies the pathogenesis of numerous
chronic pulmonary diseases including chronic obstructive pulmonary disease, asthma and …
chronic pulmonary diseases including chronic obstructive pulmonary disease, asthma and …
Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis
L Wollin, E Wex, A Pautsch, G Schnapp… - European …, 2015 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal disease
characterised by fibrosis of the lung parenchyma and loss of lung function. Although the …
characterised by fibrosis of the lung parenchyma and loss of lung function. Although the …
Inflammation and intussusceptive angiogenesis in COVID-19: everything in and out of flow
We recently showed that SARS-CoV-2 infection leads to angiocentric inflammation in COVID-
19-induced respiratory failure, with a greater number of ACE2-positive endothelial cells …
19-induced respiratory failure, with a greater number of ACE2-positive endothelial cells …
Idiopathic pulmonary fibrosis beyond the lung: understanding disease mechanisms to improve diagnosis and management
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disorder with an estimated
median survival time of 3–5 years after diagnosis. This condition occurs primarily in elderly …
median survival time of 3–5 years after diagnosis. This condition occurs primarily in elderly …
Cellular interactions in the pathogenesis of interstitial lung diseases
G Bagnato, S Harari - European Respiratory Review, 2015 - Eur Respiratory Soc
Interstitial lung disease (ILD) encompasses a large and diverse group of pathological
conditions that share similar clinical, radiological and pathological manifestations, despite …
conditions that share similar clinical, radiological and pathological manifestations, despite …
Biomarkers for the adverse effects on respiratory system health associated with atmospheric particulate matter exposure
C Guo, S Lv, Y Liu, Y Li - Journal of Hazardous Materials, 2022 - Elsevier
Large amounts of epidemiological evidence have confirmed the atmospheric particulate
matter (PM 2.5) exposure was positively correlated with the morbidity and mortality of …
matter (PM 2.5) exposure was positively correlated with the morbidity and mortality of …
Molecular pathogenesis of pulmonary fibrosis, with focus on pathways related to TGF-β and the ubiquitin-proteasome pathway
N Inui, S Sakai, M Kitagawa - International journal of molecular sciences, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease. During
the past decade, novel pathogenic mechanisms of IPF have been elucidated that have …
the past decade, novel pathogenic mechanisms of IPF have been elucidated that have …
Involvement of ER stress, PI3K/AKT activation, and lung fibroblast proliferation in bleomycin-induced pulmonary fibrosis
HS Hsu, CC Liu, JH Lin, TW Hsu, JW Hsu, K Su… - Scientific reports, 2017 - nature.com
Pulmonary fibrosis is characterized by fibroblast proliferation and extracellular matrix
remodelling, leading to respiratory insufficiency. The mechanisms underlying this …
remodelling, leading to respiratory insufficiency. The mechanisms underlying this …
Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition Are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms
L Sun, H Dong, W Zhang, N Wang, N Ni, X Bai… - DNA and cell …, 2021 - liebertpub.com
Epithelial-mesenchymal transition (EMT) induced by transforming growth factor-β1 (TGF-β1)
is thought to be involved in the pathogenesis of pulmonary fibrosis. Emerging evidence …
is thought to be involved in the pathogenesis of pulmonary fibrosis. Emerging evidence …
LRRK2 plays essential roles in maintaining lung homeostasis and preventing the development of pulmonary fibrosis
Y Tian, J Lv, Z Su, T Wu, X Li, X Hu… - Proceedings of the …, 2021 - National Acad Sciences
Perturbation of lung homeostasis is frequently associated with progressive and fatal
respiratory diseases, such as pulmonary fibrosis. Leucine-rich repeat kinase 2 (LRRK2) is …
respiratory diseases, such as pulmonary fibrosis. Leucine-rich repeat kinase 2 (LRRK2) is …