Replication factor C (RFC) family is a complex comprised of the RFC1, RFC2, RFC3, RFC4,
and RFC5 subunits, which acts as a primer recognition factor for DNA polymerase. It is …

Nuclear Receptors (NRs) are a superfamily of transcription factors specific to metazoans that
have the unique ability to directly translate the message of a signaling molecule into a …

Introduction Although some circRNAs have been found to regulate the progression of
malignancies, their functions and coupled molecular mechanisms are still unclear. In our …

Objective Head and neck squamous cell carcinoma (HNSCC) is a prevalent cancer that
originates from the squamous cells. The role of the replication factor C subunit 3 (RFC3) in …

Lung cancer is a malignant tumor responsible for the highest mortality rate in humans. The
identification of novel functional genes is of great importance in the treatment of lung cancer …

CREB (cyclic AMP response element-binding protein) is a transcription factor overexpressed
in normal and neoplastic myelopoiesis and regulates cell cycle progression, although its …

Gastric cancer (GC) is one of the major causes of death worldwide, ranking as the fifth most
incident cancer in 2020 and the fourth leading cause of cancer mortality. The majority of GC …

Deciphering the molecular networks that discriminate organ‐confined breast cancer from
metastatic breast cancer may lead to the identification of critical biomarkers for breast cancer …

The currently available medical treatment options of adrenocortical cancer (ACC) are
limited. In our previous meta-analysis of adrenocortical tumor genomics data, ACC was …

Hepatocellular carcinoma (HCC) is one of the most common and lethal malignancies
worldwide. Replication factor C (RFC) plays an important role in DNA replication and …