Background As the population ages, increasing numbers of older adults are undergoing
surgery. Frailty is prevalent in older adults and may be a better predictor of post-operative …

Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed
countries. It is characterized by progressive fibro-calcific remodelling and thickening of the …

Background Although transcatheter aortic-valve replacement (TAVR) is an accepted
alternative to surgery in patients with severe aortic stenosis who are at high surgical risk …

Background We compared transcatheter aortic-valve replacement (TAVR), using a self-
expanding transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in …

Background Based on the early results of the Placement of Aortic Transcatheter Valves
(PARTNER) trial, transcatheter aortic valve replacement (TAVR) is an accepted treatment for …

Objectives: This study sought to evaluate the safety and efficacy of the CoreValve
transcatheter heart valve (THV) for the treatment of severe aortic stenosis in patients at …

Due to the aging and increasingly complex nature of our patients, frailty has become a high-
priority theme in cardiovascular medicine. Despite the recognition of frailty as a pivotal …

Background: In patients with severe aortic stenosis at increased risk for surgery, self-
expanding transcatheter aortic valve replacement (TAVR) is associated with improved 2 …

Objective Current preoperative assessments for cardiac surgery, such as the European
System for Cardiac Operative Risk Evaluation II and the Society of Thoracic Surgeons risk …

Background: The semiquantitative Clinical Frailty Scale (CFS) is a simple tool to assess
patients' frailty and has been shown to correlate with mortality in elderly patients even when …