Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
that seriously threatens human health and life. Due to its high reactivity, cytotoxicity and …

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published the
complete 2023 GOLD report, which can be freely downloaded from its web page (www …

Background: Despite the known benefits of pulmonary rehabilitation (PR) for patients with
chronic respiratory disease, this treatment is underused. Evidence-based guidelines should …

Importance Chronic obstructive pulmonary disease (COPD) is a respiratory condition that is
associated with significant health and economic burden worldwide. Previous studies …

Most patients with chronic obstructive pulmonary disease (COPD) have at least one
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …

Pulmonary rehabilitation has established a status of evidence-based therapy for patients
with symptomatic COPD in the stable phase and after acute exacerbations. Rehabilitation …

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade proteins of the
extracellular matrix and the basement membrane. Thus, these enzymes regulate airway …

Rationale: Ensifentrine is a novel, selective, dual phosphodiesterase (PDE) 3 and PDE4
inhibitor with bronchodilator and antiinflammatory effects. Replicate phase III trials of …

Lung development starts in utero and continues during childhood through to adolescence,
reaching its peak in early adulthood. This growth is followed by gradual decline due to …