Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …
their important roles in the maintenance of nerves in both homeostasis and inflammation …
Corneal nerves and their role in dry eye pathophysiology
A Vereertbrugghen, JG Galletti - Experimental Eye Research, 2022 - Elsevier
As the cornea is densely innervated, its nerves are integral not only to its structure but also to
its pathophysiology. Corneal integrity depends on a protective tear film that is maintained by …
its pathophysiology. Corneal integrity depends on a protective tear film that is maintained by …
Coexistence of neuropathic corneal pain, corneal nerve abnormalities, depression, and low quality of life
A Leonardi, OM Feuerman, E Salami, D Lazzarini… - Eye, 2024 - nature.com
Purpose To evaluate the quality of life (QoL), mental health conditions and corneal
morphology in neuropathic corneal pain (NCP) subjects without a significant ocular surface …
morphology in neuropathic corneal pain (NCP) subjects without a significant ocular surface …
In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy
J Luzu, A Labbé, A Réaux-Le Goazigo, G Rabut… - The Ocular Surface, 2022 - Elsevier
Purpose To study changes in the subbasal nerve plexus by In vivo confocal microscopy
(IVCM) in Sjögren's Syndrome (SS) with or without associated Small Fiber Neuropathy …
(IVCM) in Sjögren's Syndrome (SS) with or without associated Small Fiber Neuropathy …
[HTML][HTML] Clinical associations of corneal neuromas with ocular surface diseases
Corneal neuromas, also termed microneuromas, refer to microscopic, irregularly-shaped
enlargements of terminal subbasal nerve endings at sites of nerve damage or injury. The …
enlargements of terminal subbasal nerve endings at sites of nerve damage or injury. The …
Transient Receptor Potential Vanilloid-1 Channels Facilitate Axonal Degeneration of Corneal Sensory Nerves in Dry Eye
M Pizzano, A Vereertbrugghen, A Cernutto… - The American Journal of …, 2024 - Elsevier
Corneal nerve impairment contributes significantly to dry eye disease (DED) symptoms and
is thought to be secondary to corneal epithelial damage. Transient receptor potential …
is thought to be secondary to corneal epithelial damage. Transient receptor potential …
Corneal nerve abnormalities in painful dry eye disease patients
A Guerrero-Moreno, H Liang, N Moreau, J Luzu… - Biomedicines, 2021 - mdpi.com
Background: This study aimed to compare the corneal nerve structural abnormalities
detected using in vivo confocal microscopy (IVCM) in patients with neuropathic corneal pain …
detected using in vivo confocal microscopy (IVCM) in patients with neuropathic corneal pain …
The utility of oral vitamin B1 and mecobalamin to improve corneal nerves in dry eye disease: an in vivo confocal microscopy study
X Ren, Y Chou, Y Wang, D Jing, Y Chen, X Li - Nutrients, 2022 - mdpi.com
Our purpose is to demonstrate the changes in cornea nerve parameters and symptoms and
signs in dry eye disease (DED) patients after oral vitamin B1 and mecobalamin treatment. In …
signs in dry eye disease (DED) patients after oral vitamin B1 and mecobalamin treatment. In …
Neuropathic corneal pain as debilitating manifestation of long-COVID
JN Woltsche, J Horwath-Winter, C Dorn… - Ocular Immunology …, 2023 - Taylor & Francis
This report illustrates the case of a female patient suffering from severe ocular discomfort,
tinnitus and ageusia, 7 months after a SARS-CoV-2 infection. The medical history implicated …
tinnitus and ageusia, 7 months after a SARS-CoV-2 infection. The medical history implicated …
Redefining our vision: an updated guide to the ocular immune system
Balanced immune responses in the eyes are crucial to preserve vision. The ocular immune
system has long been considered distinct, owing to the so-called 'immune privilege'of its …
system has long been considered distinct, owing to the so-called 'immune privilege'of its …