Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel
MS Hirsch, HF Günthard, JM Schapiro… - Clinical Infectious …, 2008 - academic.oup.com
Resistance to antiretroviral drugs remains an important limitation to successful human
immunodeficiency virus type 1 (HIV-1) therapy. Resistance testing can improve treatment …
immunodeficiency virus type 1 (HIV-1) therapy. Resistance testing can improve treatment …
Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: a systematic review …
RK Gupta, A Hill, AW Sawyer, A Cozzi-Lepri… - The Lancet infectious …, 2009 - thelancet.com
Antiretroviral-therapy rollout in resource-poor countries is often associated with limited, if
any, HIV-RNA monitoring. The effect of variable monitoring on the emergence of resistance …
any, HIV-RNA monitoring. The effect of variable monitoring on the emergence of resistance …
The World Health Organization's global strategy for prevention and assessment of HIV drug resistance
DE Bennett, S Bertagnolio, D Sutherland… - Antiviral …, 2008 - journals.sagepub.com
Antiretroviral treatment (ART) for HIV is being scaled up rapidly in resource-limited countries.
Treatment options are simplified and standardized, generally with one potent first-line …
Treatment options are simplified and standardized, generally with one potent first-line …
The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line …
MC Hosseinipour, JJG Van Oosterhout, R Weigel… - Aids, 2009 - journals.lww.com
Background: Over 150 000 Malawians have started antiretroviral therapy (ART), in which
first-line therapy is stavudine/lamivudine/nevirapine. We evaluated drug resistance patterns …
first-line therapy is stavudine/lamivudine/nevirapine. We evaluated drug resistance patterns …
Immunologic criteria are poor predictors of virologic outcome: implications for HIV treatment monitoring in resource-limited settings
HE Rawizza, B Chaplin, ST Meloni… - Clinical Infectious …, 2011 - academic.oup.com
Background. Viral load (VL) quantification is considered essential for determining
antiretroviral treatment (ART) success in resource-rich countries. However, it is not widely …
antiretroviral treatment (ART) success in resource-rich countries. However, it is not widely …
Utility of routine viral load, CD4 cell count, and clinical monitoring among adults with HIV receiving antiretroviral therapy in Uganda: randomised trial
Objective To evaluate the use of routine laboratory monitoring in terms of clinical outcomes
among patients receiving antiretroviral therapy (ART) in Uganda. Design Randomised …
among patients receiving antiretroviral therapy (ART) in Uganda. Design Randomised …
Differential persistence of transmitted HIV-1 drug resistance mutation classes
V Jain, MC Sucupira, P Bacchetti… - Journal of Infectious …, 2011 - academic.oup.com
Background. Transmitted human immunodeficiency virus type 1 (HIV-1) drug resistance
(TDR) mutations can become replaced over time by emerging wild-type viral variants with …
(TDR) mutations can become replaced over time by emerging wild-type viral variants with …
Outcomes from monitoring of patients on antiretroviral therapy in resource-limited settings with viral load, CD4 cell count, or clinical observation alone: a computer …
Background In lower-income countries, WHO recommends a population-based approach to
antiretroviral treatment with standardised regimens and clinical decision making based on …
antiretroviral treatment with standardised regimens and clinical decision making based on …
Immuno-virologic outcomes and immuno-virologic discordance among adults alive and on anti-retroviral therapy at 12 months in Nigeria
CJ Anude, E Eze, HC Onyegbutulem, M Charurat… - BMC infectious …, 2013 - Springer
Background Predictors of immuno-virologic outcomes and discordance and their
associations with clinical, demographic, socio-economic and behavioral risk factors are not …
associations with clinical, demographic, socio-economic and behavioral risk factors are not …
Lopinavir/ritonavir monotherapy or plus zidovudine and lamivudine in antiretroviral-naive HIV-infected patients
JF Delfraissy, P Flandre, C Delaugerre, J Ghosn… - Aids, 2008 - journals.lww.com
Background: Guidelines for the use of antiretroviral agents for HIV-1 infection recommend
combining at least three agents. The toxicity, cost, and complexity of such regimens warrant …
combining at least three agents. The toxicity, cost, and complexity of such regimens warrant …