Regulated cell death (RCD) in cancer: key pathways and targeted therapies

F Peng, M Liao, R Qin, S Zhu, C Peng, L Fu… - Signal transduction and …, 2022 - nature.com
Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …

Biological consequences of vanadium effects on formation of reactive oxygen species and lipid peroxidation

M Aureliano, AL De Sousa-Coelho, CC Dolan… - International Journal of …, 2023 - mdpi.com
Lipid peroxidation (LPO), a process that affects human health, can be induced by exposure
to vanadium salts and compounds. LPO is often exacerbated by oxidation stress, with some …

Vanadium: Risks and possible benefits in the light of a comprehensive overview of its pharmacotoxicological mechanisms and multi-applications with a summary of …

A Ścibior, Ł Pietrzyk, Z Plewa, A Skiba - … of Trace Elements in Medicine and …, 2020 - Elsevier
Background Vanadium (V) is an element with a wide range of effects on the mammalian
organism. The ability of this metal to form organometallic compounds has contributed to the …

Molecular and cellular mechanisms of cytotoxic activity of vanadium compounds against cancer cells

S Kowalski, D Wyrzykowski, I Inkielewicz-Stępniak - Molecules, 2020 - mdpi.com
Discovering that metals are essential for the structure and function of biomolecules has
given a completely new perspective on the role of metal ions in living organisms. Nowadays …

Acute toxicity evaluation of non-innocent oxidovanadium (V) schiff base complex

LMA Lima, H Murakami, DJ Gaebler, WE Silva… - Inorganics, 2021 - mdpi.com
The vanadium (V) complexes have been investigated as potential anticancer agents which
makes it essential to evaluate their toxicity for safe use in the clinic. The large-scale …

Effect of the extra-nuclear cation on the cytotoxicity and mechanism of action of pyridine-2, 6-dicarboxylate Ga (III) complexes

S Khaksar, A Aliabadi, A Panjehpour, S Abdolmaleki - Toxicology, 2023 - Elsevier
Abstract Two Ga (III) complexes (C1) and (C2) were prepared by the one-pot reaction of
pyridine-2, 6-dicarboxylic acid and aminopyridine derivatives with gallium (III) nitrate …

Metabarcoding Reveals Temporal Patterns of Community Composition and Realized Thermal Niches of Thalassiosira Spp. (Bacillariophyceae) from the Narragansett …

TA Rynearson, SA Flickinger, DN Fontaine - Biology, 2020 - mdpi.com
Diatoms generate nearly half of marine primary production and are comprised of a diverse
array of species that are often morphologically cryptic or difficult to identify using light …

The role of autophagy in pancreatic cancer—Recent advances

M New, S Tooze - Biology, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers with a 5-
year survival rate of only 9%, despite ongoing efforts to improve treatment. This dismal …

Trace elements in pancreatic cancer

Y Yanjun, Z Jing, S Yifei, G Gangzhao… - Cancer …, 2024 - Wiley Online Library
Background Pancreatic cancer (PCA) is an extremely aggressive malignant cancer with an
increasing incidence and a low five‐year survival rate. The main reason for this high …

Vanadium complex as a potential modulator of the autophagic mechanism through proteins PI3K and ULK1: Development, validation and biological implications of a …

TMR Santos, CA Tavares, EFF da Cunha… - Journal of …, 2024 - Taylor & Francis
The modulation of autophagy has been presented as a very useful strategy in anticancer
treatments. In this sense, the vanadium complex (VC) bis (2, 2'-bipyridine) …