A comprehensive review on steroidal bioconjugates as promising leads in drug discovery
R Bansal, A Suryan - ACS bio & med Chem Au, 2022 - ACS Publications
Ever increasing unmet medical requirements of the human race and the continuous fight for
survival against variety of diseases give birth to novel molecules through research. As …
survival against variety of diseases give birth to novel molecules through research. As …
Recent advances in steroid amino acid conjugates: Old scaffolds with new dimensions
P Singla, DB Salunke - European Journal of Medicinal Chemistry, 2020 - Elsevier
Hybrid chemical compounds formed by conjugation of two or more bioactive molecules have
shown wide variety of applications in biology, microelectronics as well as material sciences …
shown wide variety of applications in biology, microelectronics as well as material sciences …
Synthesis and antimicrobial activity of β-lactam–bile acid conjugates linked via triazole
NS Vatmurge, BG Hazra, VS Pore, F Shirazi… - Bioorganic & medicinal …, 2008 - Elsevier
Synthesis of novel 1, 2, 3-triazole-linked β-lactam–bile acid conjugates 17–24 using 1, 3-
dipolar cycloaddition reaction of azido β-lactam and terminal alkyne of bile acids in the …
dipolar cycloaddition reaction of azido β-lactam and terminal alkyne of bile acids in the …
Sterol-modified phospholipids: cholesterol and phospholipid chimeras with improved biomembrane properties
Z Huang, FC Szoka Jr - Journal of the American Chemical Society, 2008 - ACS Publications
We synthesized a family of sterol-modified glycerophospholipids (SML) in which the sn-1 or
sn-2 position is covalently attached to cholesterol and the alternative position contains an …
sn-2 position is covalently attached to cholesterol and the alternative position contains an …
Design and synthesis of fluconazole/bile acid conjugate using click reaction
Novel fluconazole/bile acid conjugates were designed and their regioselective synthesis
was achieved in very high yield via Cu (I) catalyzed intermolecular 1, 3-dipolar …
was achieved in very high yield via Cu (I) catalyzed intermolecular 1, 3-dipolar …
The structural diversity and biological activity of steroid oximes
AR Gomes, AS Pires, FMF Roleira… - Molecules, 2023 - mdpi.com
Steroids and their derivatives have been the subject of extensive research among
investigators due to their wide range of pharmacological properties, in which steroidal …
investigators due to their wide range of pharmacological properties, in which steroidal …
A multiple multicomponent approach to chimeric peptide–peptoid podands
DG Rivera, F León, O Concepción… - … A European Journal, 2013 - Wiley Online Library
The success of multi‐armed, peptide‐based receptors in supramolecular chemistry
traditionally is not only based on the sequence but equally on an appropriate positioning of …
traditionally is not only based on the sequence but equally on an appropriate positioning of …
Facially amphiphilic cholic acid–lysine conjugates as promising antimicrobials
The emergence of multidrug-resistant microbes is a significant health concern posing a
constant need for new antimicrobials. Membrane-targeting antibiotics are promising …
constant need for new antimicrobials. Membrane-targeting antibiotics are promising …
Synthesis and selective anticancer activity of steroidal glycoconjugates
MA Fernández-Herrera, H López-Muñoz… - European journal of …, 2012 - Elsevier
The synthesis of glucosamine derivatives of the steroidal sapogenins diosgenin and
hecogenin using the N-phthaloyl protected trichloroacetimidate of d-glucosamine as donor …
hecogenin using the N-phthaloyl protected trichloroacetimidate of d-glucosamine as donor …
A Multicomponent Conjugation Strategy to Unique N‐Steroidal Peptides: First Evidence of the Steroidal Nucleus as a β‐Turn Inducer in Acyclic Peptides
Constraining small peptides into specific secondary structures has been a major challenge
in peptide ligand design. So far, the major solution for decreasing the conformational …
in peptide ligand design. So far, the major solution for decreasing the conformational …