The role of Dental-derived stem cell-based therapy and their derived extracellular vesicles in post-COVID-19 syndrome-induced tissue damage

M Rostami, P Farahani, S Esmaelian, Z Bahman… - Stem Cell Reviews and …, 2024 - Springer
Abstract Long coronavirus disease 2019 (COVID-19) is linked to an increased risk of post-
acute sequelae affecting the pulmonary and extrapulmonary organ systems. Up to 20% of …

A glimpse into viral warfare: decoding the intriguing role of highly pathogenic coronavirus proteins in apoptosis regulation

L Cheng, Y Rui, Y Wang, S Chen, J Su… - Journal of Biomedical …, 2024 - Springer
Coronaviruses employ various strategies for survival, among which the activation of
endogenous or exogenous apoptosis stands out, with viral proteins playing a pivotal role …

MYC: there is more to it than cancer

MF Zacarías-Fluck, L Soucek… - Frontiers in Cell and …, 2024 - frontiersin.org
MYC is a pleiotropic transcription factor involved in multiple cellular processes. While its
mechanism of action and targets are not completely elucidated, it has a fundamental role in …

SARS-CoV-2 envelope protein regulates innate immune tolerance

ES Geanes, R McLennan, SH Pierce, HL Menden… - Iscience, 2024 - cell.com
Severe COVID-19 often leads to secondary infections and sepsis that contribute to long
hospital stays and mortality. However, our understanding of the precise immune …

Unraveling the structural and functional dimensions of SARS-CoV2 proteins in the context of COVID-19 pathogenesis and therapeutics

A Jhanwar, D Sharma, U Das - International Journal of Biological …, 2024 - Elsevier
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) has emerged as
the causative agent behind the global pandemic of Coronavirus Disease 2019 (COVID-19) …

[HTML][HTML] The role of Helicobacter pylori in augmenting the severity of SARS-CoV-2 related gastrointestinal symptoms: An insight from molecular mechanism of co …

A Tandon, B Baral, V Saini, M Kandpal, AK Dixit… - Heliyon, 2024 - cell.com
Coinfection of pathogenic bacteria and viruses is associated with multiple diseases. During
the COVID-19 pandemic, the co-infection of other pathogens with SARS-CoV-2 was one of …

Exploring Myc puzzle: Insights into cancer, stem cell biology, and PPI networks

N Ghasemi, H Azizi - Gene, 2024 - Elsevier
Abstract “The grand orchestrator,”“Universal Amplifier,”“double-edged sword,” and
“Undruggable” are just some of the Myc oncogene so-called names. It has been around 40 …

Ferroptosis: a potential target for acute lung injury

Y Wen, Y Liu, W Liu, W Liu, J Dong, Q Liu, Z Yu… - Inflammation …, 2024 - Springer
Acute lung injury (ALI) is caused by a variety of intrapulmonary and extrapulmonary factors
and is associated with high morbidity and mortality. Oxidative stress is an important part of …

Targeting SMYD2 promotes ferroptosis and impacts the progression of pancreatic cancer through the c-Myc/NCOA4 axis-mediated ferritinophagy

J Tan, S Liao, B Yuan, X Liu, W Yu, H Zhan… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background Pancreatic cancer (PC) is characterized by a poor prognosis and limited
treatment options. Ferroptosis plays an important role in cancer, SET and MYND domain …

The Y498T499-SARS-CoV-2 Spike (S) protein variant interacts with rat ACE2 but does not infect or induce responses in the rat lung when delivered as a S-protein …

AL Green, D Debellis, E Cowell… - Access …, 2024 - microbiologyresearch.org
The rat is a useful laboratory model for respiratory disease, and SARS-CoV-2 proteins such
as the spike (S) protein can induce inflammation. This study has investigated the ability of …