Umbilical cord blood transplantation: the first 25 years and beyond

KK Ballen, E Gluckman… - Blood, The Journal of the …, 2013 - ashpublications.org
Umbilical cord blood is an alternative hematopoietic stem cell source for patients with
hematologic diseases who can be cured by allogeneic hematopoietic cell transplantation …

[HTML][HTML] Optimal practices in unrelated donor cord blood transplantation for hematologic malignancies

JN Barker, J Kurtzberg, K Ballen, M Boo… - Biology of Blood and …, 2017 - Elsevier
Unrelated donor cord blood transplantation (CBT) results in disease-free survival
comparable to that of unrelated adult donor transplantation in patients with hematologic …

Impact of allele-level HLA matching on outcomes after myeloablative single unit umbilical cord blood transplantation for hematologic malignancy

M Eapen, JP Klein, A Ruggeri… - Blood, The Journal …, 2014 - ashpublications.org
We studied the effect of allele-level matching at human leukocyte antigen (HLA)-A,-B,-C, and-
DRB1 in 1568 single umbilical cord blood (UCB) transplantations for hematologic …

Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemia

A Scaradavou, CG Brunstein, M Eapen… - Blood, The Journal …, 2013 - ashpublications.org
Cell dose is a major limitation for umbilical cord blood (UCB) transplantation because units
containing a minimum of 2.5× 107 total nucleated cells (TNC)/kilogram patient body weight …

Donor-specific anti-HLA antibodies predict outcome in double umbilical cord blood transplantation

C Cutler, HT Kim, L Sun, D Sese… - Blood, The Journal …, 2011 - ashpublications.org
Using a uniform detection method for donor-specific anti-HLA antibodies (DSAs), we sought
to determine the effect of preformed DSAs on outcomes in double umbilical cord blood …

Selection of optimal alternative graft source: mismatched unrelated donor, umbilical cord blood, or haploidentical transplant

KK Ballen, J Koreth, YB Chen, BR Dey… - Blood, The Journal of …, 2012 - ashpublications.org
Only 30% of patients who require an allogeneic hematopoietic cell transplant will have an
HLA-matched sibling donor. A search for an unrelated donor will be undertaken for patients …

Allogeneic hematopoietic cell transplantation; the current renaissance

EA Copelan, A Chojecki, HM Lazarus, BR Avalos - Blood Reviews, 2019 - Elsevier
Allogeneic hematopoietic cell transplantation (HCT) provides the best chance for cure for
many patients with malignant and nonmalignant hematologic disorders. Recent advances in …

[HTML][HTML] Guidelines for cord blood unit selection

I Politikos, E Davis, M Nhaissi, JE Wagner… - Biology of Blood and …, 2020 - Elsevier
Optimal cord blood (CB) unit selection is critical to maximize the likelihood of successful
engraftment and survival after CB transplantation (CBT). However, unit selection can be …

High day 28 ST2 levels predict for acute graft-versus-host disease and transplant-related mortality after cord blood transplantation

DM Ponce, P Hilden, C Mumaw… - Blood, The Journal …, 2015 - ashpublications.org
While cord blood transplantation (CBT) is an effective therapy for hematologic malignancies,
acute graft-versus-host disease (aGVHD) is a leading cause of transplant-related mortality …

Racial disparities in access to HLA-matched unrelated donor transplants: a prospective 1312-patient analysis

JN Barker, K Boughan, PB Dahi, SM Devlin… - Blood …, 2019 - ashpublications.org
Abstract Availability of 8/8 HLA-allele matched unrelated donors (URDs) is a barrier for
ethnic and racial minorities. We prospectively evaluated receipt of 8/8 HLA-allele matched …