Phylogenetic tree building in the genomic age

P Kapli, Z Yang, MJ Telford - Nature Reviews Genetics, 2020 - nature.com
Knowing phylogenetic relationships among species is fundamental for many studies in
biology. An accurate phylogenetic tree underpins our understanding of the major transitions …

A brief history of bioinformatics

J Gauthier, AT Vincent, SJ Charette… - Briefings in …, 2019 - academic.oup.com
It is easy for today's students and researchers to believe that modern bioinformatics
emerged recently to assist next-generation sequencing data analysis. However, the very …

MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization

K Katoh, J Rozewicki, KD Yamada - Briefings in bioinformatics, 2019 - academic.oup.com
This article describes several features in the MAFFT online service for multiple sequence
alignment (MSA). As a result of recent advances in sequencing technologies, huge numbers …

The clustal omega multiple alignment package

F Sievers, DG Higgins - Multiple sequence alignment: Methods and …, 2021 - Springer
Clustal Omega is a version, completely rewritten and revised in 2011, of the widely used
Clustal series of programs for multiple sequence alignment. It can deal with very large …

DeepTracer for fast de novo cryo-EM protein structure modeling and special studies on CoV-related complexes

J Pfab, NM Phan, D Si - Proceedings of the National …, 2021 - National Acad Sciences
Information about macromolecular structure of protein complexes and related cellular and
molecular mechanisms can assist the search for vaccines and drug development processes …

[HTML][HTML] Protein secondary structure prediction using deep convolutional neural fields

S Wang, J Peng, J Ma, J Xu - Scientific reports, 2016 - nature.com
Protein secondary structure (SS) prediction is important for studying protein structure and
function. When only the sequence (profile) information is used as input feature, currently the …

A simple method to control over-alignment in the MAFFT multiple sequence alignment program

K Katoh, DM Standley - Bioinformatics, 2016 - academic.oup.com
Motivation: We present a new feature of the MAFFT multiple alignment program for
suppressing over-alignment (aligning unrelated segments). Conventional MAFFT is highly …

GenASM: A high-performance, low-power approximate string matching acceleration framework for genome sequence analysis

DS Cali, GS Kalsi, Z Bingöl, C Firtina… - 2020 53rd Annual …, 2020 - ieeexplore.ieee.org
Genome sequence analysis has enabled significant advancements in medical and scientific
areas such as personalized medicine, outbreak tracing, and the understanding of evolution …

MAFFT multiple sequence alignment software version 7: improvements in performance and usability

K Katoh, DM Standley - Molecular biology and evolution, 2013 - academic.oup.com
We report a major update of the MAFFT multiple sequence alignment program. This version
has several new features, including options for adding unaligned sequences into an existing …

[HTML][HTML] Gut microbiome function predicts response to anti-integrin biologic therapy in inflammatory bowel diseases

AN Ananthakrishnan, C Luo, V Yajnik, H Khalili… - Cell host & …, 2017 - cell.com
The gut microbiome plays a central role in inflammatory bowel diseases (IBDs)
pathogenesis and propagation. To determine whether the gut microbiome may predict …