Convergent evolution of toxin resistance in animals
Convergence is the phenomenon whereby similar phenotypes evolve independently in
different lineages. One example is resistance to toxins in animals. Toxins have evolved …
different lineages. One example is resistance to toxins in animals. Toxins have evolved …
Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: A comprehensive review
B Lomonte - Toxicon, 2023 - Elsevier
Muscle necrosis is a potential clinical complication of snakebite envenomings, which in
severe cases can lead to functional or physical sequelae such as disability or amputation …
severe cases can lead to functional or physical sequelae such as disability or amputation …
Coevolution takes the sting out of it: Evolutionary biology and mechanisms of toxin resistance in animals
Understanding how biotic interactions shape the genomes of the interacting species is a
long-sought goal of evolutionary biology that has been hampered by the scarcity of tractable …
long-sought goal of evolutionary biology that has been hampered by the scarcity of tractable …
Natural phospholipase A2 myotoxin inhibitor proteins from snakes, mammals and plants
A renewed interest in the phenomenon of inter-and intra-species resistance towards the
toxicity of snake venoms, coupled with the search for new strategies for treatment of snake …
toxicity of snake venoms, coupled with the search for new strategies for treatment of snake …
Effects of aqueous extract of Casearia sylvestris (Flacourtiaceae) on actions of snake and bee venoms and on activity of phospholipases A2
The crude aqueous extract from the leaves of Casearia sylvestris, a plant found in Brazilian
open pastures, was assayed for its ability to inhibit phospholipase A2 (PLA2) activity and …
open pastures, was assayed for its ability to inhibit phospholipase A2 (PLA2) activity and …
Neutralization of proteases from Bothrops snake venoms by the aqueous extract from Casearia sylvestris (Flacourtiaceae)
Aqueous extract from Casearia sylvestris leaves, a typical plant from Brazilian open
pastures, was able to neutralize the hemorrhagic activity caused by Bothrops asper …
pastures, was able to neutralize the hemorrhagic activity caused by Bothrops asper …
The molecular basis of venom resistance in a rattlesnake‐squirrel predator‐prey system
Understanding how interspecific interactions mould the molecular basis of adaptations in
coevolving species is a long‐sought goal of evolutionary biology. Venom in predators and …
coevolving species is a long‐sought goal of evolutionary biology. Venom in predators and …
Snake venom phospholipase A2 inhibitors: medicinal chemistry and therapeutic potential
S Marcussi, CD Sant'Ana, CZ Oliveira… - Current topics in …, 2007 - ingentaconnect.com
Phospholipases A2 (PLA2s) are commonly found in snake venoms from Viperidae,
Hydrophidae and Elaphidae families and have been extensively studied due to their …
Hydrophidae and Elaphidae families and have been extensively studied due to their …
Natural protease inhibitors to hemorrhagins in snake venoms and their potential use in medicine
JC Pérez, EE Sánchez - Toxicon, 1999 - Elsevier
Snake venoms are complex mixtures of many toxins and enzymes which effectively
immobilize prey without a struggle and assist in digestion. Certain animals have a …
immobilize prey without a struggle and assist in digestion. Certain animals have a …
Natural inhibitors of snake venom hemorrhagic metalloproteinases
J Perales, AGC Neves-Ferreira, RH Valente… - Toxicon, 2005 - Elsevier
Metalloproteinases play an important role in the poisoning process by snake venoms. They
evoke systemic injury, by degrading or activating host blood factors, and local damage by …
evoke systemic injury, by degrading or activating host blood factors, and local damage by …