Cation-chloride cotransporters in neuronal development, plasticity and disease
Electrical activity in neurons requires a seamless functional coupling between
plasmalemmal ion channels and ion transporters. Although ion channels have been studied …
plasmalemmal ion channels and ion transporters. Although ion channels have been studied …
Genetic and activity-dependent mechanisms underlying interneuron diversity
The proper construction of neural circuits requires the generation of diverse cell types, their
distribution to defined regions, and their specific and appropriate wiring. A major objective in …
distribution to defined regions, and their specific and appropriate wiring. A major objective in …
Interneuron types as attractors and controllers
Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …
challenging us to appropriately classify them. We previously suggested that interneuron …
Spontaneous neuronal activity in developing neocortical networks: from single cells to large-scale interactions
HJ Luhmann, A Sinning, JW Yang… - Frontiers in neural …, 2016 - frontiersin.org
Neuronal activity has been shown to be essential for the proper formation of neuronal
circuits, affecting developmental processes like neurogenesis, migration, programmed cell …
circuits, affecting developmental processes like neurogenesis, migration, programmed cell …
NKCC1 chloride importer antagonists attenuate many neurological and psychiatric disorders
Y Ben-Ari - Trends in neurosciences, 2017 - cell.com
In physiological conditions, adult neurons have low intracellular Cl−[(Cl−) I] levels
underlying the γ-aminobutyric acid (GABA) ergic inhibitory drive. In contrast, neurons have …
underlying the γ-aminobutyric acid (GABA) ergic inhibitory drive. In contrast, neurons have …
Neurogenesis in the developing and adult brain—similarities and key differences
M Götz, M Nakafuku, D Petrik - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Adult neurogenesis in the mammalian brain is often viewed as a continuation of
neurogenesis at earlier, developmental stages. Here, we will critically review the extent to …
neurogenesis at earlier, developmental stages. Here, we will critically review the extent to …
Neuronal activity patterns in the developing barrel cortex
HJ Luhmann, R Khazipov - Neuroscience, 2018 - Elsevier
The developing barrel cortex reveals a rich repertoire of neuronal activity patterns, which
have been also found in other sensory neocortical areas and in other species including the …
have been also found in other sensory neocortical areas and in other species including the …
A transient translaminar GABAergic interneuron circuit connects thalamocortical recipient layers in neonatal somatosensory cortex
GABAergic activity is thought to influence developing neocortical sensory circuits. Yet the
late postnatal maturation of local layer (L) 4 circuits suggests alternate sources of GABAergic …
late postnatal maturation of local layer (L) 4 circuits suggests alternate sources of GABAergic …
Somatostatin and somatostatin-containing neurons in shaping neuronal activity and plasticity
M Liguz-Lecznar, J Urban-Ciecko… - Frontiers in neural circuits, 2016 - frontiersin.org
Since its discovery over four decades ago, somatostatin (SOM) receives growing scientific
and clinical interest. Being localized in the nervous system in a subset of interneurons …
and clinical interest. Being localized in the nervous system in a subset of interneurons …
Control of cortical neuronal migration by glutamate and GABA
HJ Luhmann, A Fukuda, W Kilb - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Neuronal migration in the cortex is controlled by the paracrine action of the classical
neurotransmitters glutamate and GABA. Glutamate controls radial migration of pyramidal …
neurotransmitters glutamate and GABA. Glutamate controls radial migration of pyramidal …