TLR9: a friend or a foe

MM Saber, N Monir, AS Awad, ME Elsherbiny, HF Zaki - Life Sciences, 2022 - Elsevier
The innate immune system is a primary protective line in our body. It confers its protection
through different pattern recognition receptors (PRRs), especially toll like receptors (TLRs) …

Relationship between the thrombospondin-1/Toll-like receptor 4 (TSP1/TLR4) pathway and vitamin D levels in obese and normal weight subjects with different …

EY Khairy, A Saad - The Journal of Physiological Sciences, 2023 - Springer
Abstract Thrombospondin-1 (TSP1) contributes to obesity-associated inflammation via
activating Toll-like receptor 4 (TLR4). The regulatory role of vitamin D on this pathway has …

[PDF][PDF] Estimation of Serum TLR-9, TNF-α, and IL-6 Levels in the Iraqi Patients Diagnosed as Acute Myelogenous Leukemia

MQ Mohammed, AH Alwan, AA Almukhtar - Baghdad Sci J, 2024 - iasj.net
Acute myelogenous leukemia (AML) is a varied group of biological and clinical diseases. It
is distinguished by the fast proliferation of aberrant cells in the bone marrow, which …

Revealing of TLR-9 gene polymorphisms by qPCR HRM technique and their influence on TLR-9 serum level in acute myeloid leukemia patients: Case-control study

MQ Mohammed, AH Alwan, AA Almukhtar… - Cytokine, 2024 - Elsevier
Acute myeloid leukemia (AML) is one of the most common and fatal malignancies that affect
adults, which can quickly become aggressive if left untreated, and leukemia cells invade the …

Immunological Role of Toll-Like Receptor Markers (TLR2 and TLR4) in Patients with Helicobacter pylori infection at Basrah, Iraq

RA Kareem - Archives of Razi Institute, 2023 - pmc.ncbi.nlm.nih.gov
Helicobacter pylori is a spiral-shaped, flagellated, microaerophilic bacteria found in the
human gastric sub-mucosa. This study aimed to investigate the association between toll-like …

Evaluation of the level of tumor necrosis factor-alpha and lactate dehydrogenase in acute lymphoblastic leukemia patients

RY Ahmed, ZI Al Hatem - Iraqi Journal of Hematology, 2024 - journals.lww.com
BACKGROUND: Acute lymphoblastic leukemia (ALL) is an abnormal clonal proliferation of
early hemopoietic precursor cells in bone marrow (BM). There are certain cytokines like …

[PDF][PDF] Evaluation of FOXP3 and IL10 as immunosuppressant markers in pediatric acute lymphocytic leukemia patients in Iraq.

ZJ Mohammed, MK Zughair, MN Humoud… - Romanian Journal of …, 2024 - rjp.com.ro
ABSTRACT Background. Increased FOXP3+ Treg levels in the TME were positively
correlated with a worse prognosis in certain cancer patients. FOXP3 was significantly …

Association of GATA3 Rs3824662 Gene Polymorphism with Response to Induction Therapy in Acute Lymphoblastic Leukemia

AM Salih, JNJ Alalsaidissa - The Egyptian Journal of Hospital …, 2023 - ejhm.journals.ekb.eg
Background: The malignant transformation and multiplication of lymphoid precursor cells in
the bone marrow, blood, and extramedullary tissues is known as acute lymphoblastic …

Impact of Gene Expression of TLR4, TLR7, and TLR9 in Children with Acute Lymphocytic Leukemia in Basrah

RA Mustafa, HA Jasim, SK Al-Salait - Iranian Journal of War and Public …, 2022 - ijwph.ir
Aims: Acute lymphoblastic leukemia (ALL) is the most prevalent malignancy in children,
accounting for up to 25% of all malignancies in children under the age of 15. TLRs are …