BRPF1-KAT6A/KAT6B complex: molecular structure, biological function and human disease
G Zu, Y Liu, J Cao, B Zhao, H Zhang, L You - Cancers, 2022 - mdpi.com
Simple Summary BRPF1 (also named as BR140) was identified 28 years ago, and it was not
until the past 5 years that its mutations in humans caught increasing attention. Those …
until the past 5 years that its mutations in humans caught increasing attention. Those …
[HTML][HTML] Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7
In the conventional model of transcriptional activation, transcription factors bind to response
elements and recruit co-factors, including histone acetyltransferases. Contrary to this model …
elements and recruit co-factors, including histone acetyltransferases. Contrary to this model …
HBO1, a MYSTerious KAT and its links to cancer
The histone acetyltransferase HBO1, also known as KAT7, is a major chromatin modifying
enzyme responsible for H3 and H4 acetylation. It is found within two distinct tetrameric …
enzyme responsible for H3 and H4 acetylation. It is found within two distinct tetrameric …
The circular RNA Rap1b promotes Hoxa5 transcription by recruiting Kat7 and leading to increased Fam3a expression, which inhibits neuronal apoptosis in acute …
FF Zhang, L Zhang, L Zhao, Y Lu, X Dong… - Neural Regeneration …, 2023 - journals.lww.com
Circular RNAs can regulate the development and progression of ischemic cerebral disease.
However, it remains unclear whether they play a role in acute ischemic stroke. To investigate …
However, it remains unclear whether they play a role in acute ischemic stroke. To investigate …
Molecular Characteristics and Therapeutic Vulnerabilities of Claudin-low Breast Cancers Derived from Cell Line Models
IA Voutsadakis - Cancer Genomics & Proteomics, 2023 - cgp.iiarjournals.org
Abstract Background/Aim: Breast cancers constitute heterogeneous tumor groups and their
categorization in subtypes based on the expression of the estrogen (ER), progesterone (PR) …
categorization in subtypes based on the expression of the estrogen (ER), progesterone (PR) …
[PDF][PDF] KAT7 促进软骨细胞衰老
王旭蕾， 储柱平， 王惠敏， 魏伟， 严尚学 - 安徽医科大学学报, 2024 - aydxb.cn
摘要目的建立过度复制诱导原代小鼠软骨细胞衰老模型及小鼠自然衰老模型, 研究KAT7
在软骨细胞及组织衰老中的作用. 方法二型胶原酶消化法获取小鼠膝关节软骨细胞 …
在软骨细胞及组织衰老中的作用. 方法二型胶原酶消化法获取小鼠膝关节软骨细胞 …
Circular RNA Rap1b promotes Hoxa5 histone acetylation by recruiting Kat7 to inhibit neuronal apoptosis in acute ischemic stroke
F Zhang, L Zhao, Y Lu, X Dong, Y Liu, Y Li, S Guo… - 2022 - researchsquare.com
Stroke is a common neurological disease and one of the major causes of permanent
morbidity and disability worldwide. Although many drugs have shown significant …
morbidity and disability worldwide. Although many drugs have shown significant …
The people behind the papers–Zoe Grant, Tim Thomas, Anne Voss and Leigh Coultas
A Voss - 2021 - journals.biologists.com
The histone acetyltransferase HBO1 (KAT1) is required for histone H3 lysine 14 acetylation,
which is crucial for embryonic development. A new paper in Development reveals that, in the …
which is crucial for embryonic development. A new paper in Development reveals that, in the …