Fighting age-related orthopedic diseases: focusing on ferroptosis
Q Ru, Y Li, W Xie, Y Ding, L Chen, G Xu, Y Wu… - Bone research, 2023 - nature.com
Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation
and lipid peroxidation. It is closely related to multiple biological processes, including iron …
and lipid peroxidation. It is closely related to multiple biological processes, including iron …
The role of iron in cancer progression
Q Guo, L Li, S Hou, Z Yuan, C Li, W Zhang… - Frontiers in …, 2021 - frontiersin.org
Iron is an essential trace element for the human body, and its deficiency or excess can
induce a variety of biological processes. Plenty of evidences have shown that iron …
induce a variety of biological processes. Plenty of evidences have shown that iron …
Applications of metals for bone regeneration
K Glenske, P Donkiewicz, A Köwitsch… - International journal of …, 2018 - mdpi.com
The regeneration of bone tissue is the main purpose of most therapies in dental medicine.
For bone regeneration, calcium phosphate (CaP)-based substitute materials based on …
For bone regeneration, calcium phosphate (CaP)-based substitute materials based on …
Effects of thirty elements on bone metabolism
M Dermience, G Lognay, F Mathieu… - Journal of Trace Elements …, 2015 - Elsevier
The human skeleton, made of 206 bones, plays vital roles including supporting the body,
protecting organs, enabling movement, and storing minerals. Bones are made of organic …
protecting organs, enabling movement, and storing minerals. Bones are made of organic …
Influence of iron on bone homeostasis
Bone homeostasis is a complex process, wherein osteoclasts resorb bone and osteoblasts
produce new bone tissue. For the maintenance of skeletal integrity, this sequence has to be …
produce new bone tissue. For the maintenance of skeletal integrity, this sequence has to be …
Bone loss caused by iron overload in a murine model: importance of oxidative stress
J Tsay, Z Yang, FP Ross… - Blood, the Journal of …, 2010 - ashpublications.org
Osteoporosis is a frequent problem in disorders characterized by iron overload, such as the
thalassemias and hereditary hemochromatosis. The exact role of iron in the development of …
thalassemias and hereditary hemochromatosis. The exact role of iron in the development of …
Iron homeostasis in arthropathies: From pathogenesis to therapeutic potential
K Sun, Z Guo, L Hou, J Xu, T Du, T Xu, F Guo - Ageing Research Reviews, 2021 - Elsevier
Iron is an essential element for proper functioning of cells within mammalian organ systems;
in particular, iron homeostasis is critical for joint health. Excess iron can induce oxidative …
in particular, iron homeostasis is critical for joint health. Excess iron can induce oxidative …
Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage
BACKGROUND: Ferritin structure is designed to maintain large amounts of iron in a compact
and bioavailable form in solution. All ferritins induce fast Fe (II) oxidation in a reaction …
and bioavailable form in solution. All ferritins induce fast Fe (II) oxidation in a reaction …
Iron, zinc, copper, cadmium, mercury, and bone tissue
Ż Ciosek, K Kot, I Rotter - … Journal of Environmental Research and Public …, 2023 - mdpi.com
The paper presents the current understanding on the effects of five metals on bone tissue,
namely iron, zinc, copper, cadmium, and mercury. Iron, zinc, and copper contribute …
namely iron, zinc, copper, cadmium, and mercury. Iron, zinc, and copper contribute …
A review of biomimetic scaffolds for bone regeneration: toward a cell‐free strategy
S Jiang, M Wang, J He - Bioengineering & Translational …, 2021 - Wiley Online Library
In clinical terms, bone grafting currently involves the application of autogenous, allogeneic,
or xenogeneic bone grafts, as well as natural or artificially synthesized materials, such as …
or xenogeneic bone grafts, as well as natural or artificially synthesized materials, such as …