Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation
and lipid peroxidation. It is closely related to multiple biological processes, including iron …

Iron is an essential trace element for the human body, and its deficiency or excess can
induce a variety of biological processes. Plenty of evidences have shown that iron …

The regeneration of bone tissue is the main purpose of most therapies in dental medicine.
For bone regeneration, calcium phosphate (CaP)-based substitute materials based on …

The human skeleton, made of 206 bones, plays vital roles including supporting the body,
protecting organs, enabling movement, and storing minerals. Bones are made of organic …

Bone homeostasis is a complex process, wherein osteoclasts resorb bone and osteoblasts
produce new bone tissue. For the maintenance of skeletal integrity, this sequence has to be …

Osteoporosis is a frequent problem in disorders characterized by iron overload, such as the
thalassemias and hereditary hemochromatosis. The exact role of iron in the development of …

Iron is an essential element for proper functioning of cells within mammalian organ systems;
in particular, iron homeostasis is critical for joint health. Excess iron can induce oxidative …

BACKGROUND: Ferritin structure is designed to maintain large amounts of iron in a compact
and bioavailable form in solution. All ferritins induce fast Fe (II) oxidation in a reaction …

The paper presents the current understanding on the effects of five metals on bone tissue,
namely iron, zinc, copper, cadmium, and mercury. Iron, zinc, and copper contribute …

In clinical terms, bone grafting currently involves the application of autogenous, allogeneic,
or xenogeneic bone grafts, as well as natural or artificially synthesized materials, such as …