[HTML][HTML] Global colorectal cancer burden in 2020 and projections to 2040
As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …
Clinical value of consensus molecular subtypes in colorectal cancer: a systematic review and meta-analysis
S Ten Hoorn, TR de Back… - JNCI: Journal of the …, 2022 - academic.oup.com
Background The consensus molecular subtypes (CMSs) of colorectal cancer (CRC) capture
tumor heterogeneity at the gene-expression level. Currently, a restricted number of …
tumor heterogeneity at the gene-expression level. Currently, a restricted number of …
Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer
Z Liu, L Liu, S Weng, C Guo, Q Dang, H Xu… - Nature …, 2022 - nature.com
Long noncoding RNAs (lncRNAs) are recently implicated in modifying immunology in
colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs …
colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs …
Circadian rhythm-related genes index: A predictor for HNSCC prognosis, immunotherapy efficacy, and chemosensitivity
H Chi, J Yang, G Peng, J Zhang, G Song, X Xie… - Frontiers in …, 2023 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCC) is the most common head
and neck cancer and is highly aggressive and heterogeneous, leading to variable prognosis …
and neck cancer and is highly aggressive and heterogeneous, leading to variable prognosis …
Cuproptosis-associated lncRNA establishes new prognostic profile and predicts immunotherapy response in clear cell renal cell carcinoma
S Xu, D Liu, T Chang, X Wen, S Ma, G Sun… - Frontiers in …, 2022 - frontiersin.org
Background: Clear cell renal cell carcinoma (ccRCC) accounts for 80% of all kidney cancers
and has a poor prognosis. Recent studies have shown that copper-dependent, regulated …
and has a poor prognosis. Recent studies have shown that copper-dependent, regulated …
[HTML][HTML] Immune-related lncRNA to construct novel signature and predict the immune landscape of human hepatocellular carcinoma
W Hong, L Liang, Y Gu, Z Qi, H Qiu, X Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
The signature composed of immune-related long noncoding ribonucleic acids (irlncRNAs)
with no requirement of specific expression level seems to be valuable in predicting the …
with no requirement of specific expression level seems to be valuable in predicting the …
Cuprotosis programmed-cell-death-related lncRNA signature predicts prognosis and immune landscape in PAAD patients
H Chi, G Peng, R Wang, F Yang, X Xie, J Zhang, K Xu… - Cells, 2022 - mdpi.com
In terms of mortality and survival, pancreatic cancer is one of the worst malignancies. Known
as a unique type of programmed cell death, cuprotosis contributes to tumor cell growth …
as a unique type of programmed cell death, cuprotosis contributes to tumor cell growth …
Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer
Z Liu, CG Guo, Q Dang, L Wang, L Liu, S Weng, H Xu… - …, 2022 - thelancet.com
Summary Background Long non-coding RNAs (lncRNAs) have recently emerged as
essential biomarkers of cancer progression. However, studies are limited regarding …
essential biomarkers of cancer progression. However, studies are limited regarding …
Machine learning to construct sphingolipid metabolism genes signature to characterize the immune landscape and prognosis of patients with uveal melanoma
H Chi, G Peng, J Yang, J Zhang, G Song… - Frontiers in …, 2022 - frontiersin.org
Background Uveal melanoma (UVM) is the most common primary intraocular malignancy in
adults and is highly metastatic, resulting in a poor patient prognosis. Sphingolipid …
adults and is highly metastatic, resulting in a poor patient prognosis. Sphingolipid …
By integrating single-cell RNA-seq and bulk RNA-seq in sphingolipid metabolism, CACYBP was identified as a potential therapeutic target in lung adenocarcinoma
P Zhang, S Pei, Z Gong, Y Feng, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a heterogeneous disease with a dismal
prognosis for advanced tumors. Immune-associated cells in the microenvironment …
prognosis for advanced tumors. Immune-associated cells in the microenvironment …