INSaFLU: an automated open web-based bioinformatics suite “from-reads” for influenza whole-genome-sequencing-based surveillance

V Borges, M Pinheiro, P Pechirra, R Guiomar… - Genome Medicine, 2018 - Springer
Background A new era of flu surveillance has already started based on the genetic
characterization and exploration of influenza virus evolution at whole-genome scale …

Whole-genome-based phylogenomic analysis of the Belgian 2016–2017 influenza A (H3N2) outbreak season allows improved surveillance

LAE Van Poelvoorde, B Bogaerts, Q Fu… - Microbial …, 2021 - microbiologyresearch.org
Seasonal influenza epidemics are associated with high mortality and morbidity in the human
population. Influenza surveillance is critical for providing information to national influenza …

Randomly primed, strand-switching, MinION-based sequencing for the detection and characterization of cultured RNA viruses

KT Young, KK Lahmers, HS Sellers… - Journal of …, 2021 - journals.sagepub.com
RNA viruses rapidly mutate, which can result in increased virulence, increased escape from
vaccine protection, and false-negative detection results. Targeted detection methods have a …

Phylogenomic analysis uncovers a 9-year variation of Uganda influenza type-A strains from the WHO-recommended vaccines and other Africa strains

G Nabakooza, DC Owuor, ZR de Laurent… - Scientific Reports, 2023 - nature.com
Genetic characterisation of circulating influenza viruses directs annual vaccine strain
selection and mitigation of infection spread. We used next-generation sequencing to locally …

Evolutionary dynamics of whole-genome influenza A/H3N2 viruses isolated in Myanmar from 2015 to 2019

WW Phyu, R Saito, Y Kyaw, N Lin, SMK Win, NC Win… - Viruses, 2022 - mdpi.com
This study aimed to analyze the genetic and evolutionary characteristics of the influenza
A/H3N2 viruses circulating in Myanmar from 2015 to 2019. Whole genomes from 79 virus …

Evaluation of the added value of viral genomic information for predicting severity of influenza infection

N Van Goethem, A Robert, N Bossuyt… - BMC infectious …, 2021 - Springer
Background The severity of an influenza infection is influenced by both host and viral
characteristics. This study aims to assess the relevance of viral genomic data for the …

[HTML][HTML] Insights into Genetic and Antigenic Characteristics of Influenza A (H1N1) pdm09 Viruses Circulating in Sicily During the Surveillance Season 2023–2024: The …

F Tramuto, CM Maida, G Randazzo, A Previti… - Viruses, 2024 - mdpi.com
After disruption in the influenza circulation due to the emergence of SARS-CoV-2, the
intensity of seasonal outbreaks has returned to the pre-pandemic levels. This study aimed to …

Evolutionary analysis of seasonal influenza A viruses in Pakistan 2020–2023

N Badar, A Ikram, M Salman, S Saeed… - Influenza and Other …, 2024 - Wiley Online Library
Introduction Influenza A viruses cause global health concerns due to their high amino acid
substitution rates. They are linked to yearly seasonal epidemics and occasional pandemics …

A host-based whole genome sequencing study reveals novel risk loci associated with severity of influenza A (H1N1) pdm09 infection

M Li, Y Chen, T Chen, S Hu, L Chen… - Emerging Microbes & …, 2021 - Taylor & Francis
ABSTRACT Influenza A (H1N1) pdm09 virus has remained in a seasonal circulation since
being recognized in 2009. Although it followed a mild course in most patients, in others it …

Epidemiological and evolutionary dynamics of influenza B virus in coastal Kenya as revealed by genomic analysis of strains sampled over a single season

FM Nyasimi, DC Owuor, JM Ngoi, AG Mwihuri… - Virus …, 2020 - academic.oup.com
The genomic epidemiology of influenza B virus (IBV) remains understudied in Africa despite
significance to design of effective local and global control strategies. We undertook …