Traditional organic synthesis relies heavily on organic solvents for a multitude of tasks,
including dissolving the components and facilitating chemical reactions, because many …

The catalytic functionalization of unreactive C− H bonds has recently brought a revolution in
synthetic methodologies for the production of pharmaceuticals and natural products and for …

To improve the atom-and step-economy of organic syntheses, researchers would like to
capitalize upon the chemistry of otherwise inert carbon–hydrogen (C–H) bonds. During the …

The site-selective formation of carbonrcarbon bonds through direct functionalizations of
otherwise unreactive carbonrhydrogen bonds constitutes an economically attractive strategy …

Functionalized biaryl-containing motifs are among the most valuable synthetic scaffolds in
organic chemistry with wide ranging commercial applications in pharmaceuticals, functional …

The metal-catalysed successive activation and functionalisation of sp2 C–H bonds is the at
heart of synthetic innovations for the development of C–C bond cross-coupling processes …

Significant progress has been accomplished in direct olefinations through twofold C–H bond
functionalization of arenes and heteroarenes employing readily accessible, selective and …

Ruthenium catalysts enabled C–H bond functionalizations on arenes with challenging
secondary alkyl halides. Particularly, ruthenium (II) biscarboxylate complexes proved to be …

A selective catalytic meta sulfonation of 2-phenylpyridines was found to occur in the
presence of (arene) ruthenium (II) complexes upon reaction with sulfonyl chlorides. The 2 …

Transition metal catalyzed C–H activation has surfaced as a powerful tool to improve the
efficacy of molecular synthesis. Last two decades have witnessed a considerable progress …