Narcolepsy—clinical spectrum, aetiopathophysiology, diagnosis and treatment
CLA Bassetti, A Adamantidis, D Burdakov… - Nature Reviews …, 2019 - nature.com
Narcolepsy is a rare brain disorder that reflects a selective loss or dysfunction of orexin (also
known as hypocretin) neurons of the lateral hypothalamus. Narcolepsy type 1 (NT1) is …
known as hypocretin) neurons of the lateral hypothalamus. Narcolepsy type 1 (NT1) is …
European guideline and expert statements on the management of narcolepsy in adults and children
Background and aim Narcolepsy is an uncommon hypothalamic disorder of presumed
autoimmune origin that usually requires lifelong treatment. This paper aims to provide …
autoimmune origin that usually requires lifelong treatment. This paper aims to provide …
The immunopathogenesis of narcolepsy type 1
Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …
T cells in patients with narcolepsy target self-antigens of hypocretin neurons
Narcolepsy is a chronic sleep disorder caused by the loss of neurons that produce
hypocretin. The close association with HLA-DQB1* 06: 02, evidence for immune …
hypocretin. The close association with HLA-DQB1* 06: 02, evidence for immune …
Narcolepsy
TE Scammell - New England Journal of Medicine, 2015 - Mass Medical Soc
Narcolepsy | New England Journal of Medicine Skip to main content The New England Journal
of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical Medicine …
of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical Medicine …
[HTML][HTML] Neural network analysis of sleep stages enables efficient diagnosis of narcolepsy
Abstract Analysis of sleep for the diagnosis of sleep disorders such as Type-1 Narcolepsy
(T1N) currently requires visual inspection of polysomnography records by trained scoring …
(T1N) currently requires visual inspection of polysomnography records by trained scoring …
Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy
Narcolepsy with cataplexy is a sleep disorder caused by deficiency in the hypothalamic
neuropeptide hypocretin/orexin (HCRT), unanimously believed to result from autoimmune …
neuropeptide hypocretin/orexin (HCRT), unanimously believed to result from autoimmune …
The neurobiological basis of narcolepsy
CE Mahoney, A Cogswell, IJ Koralnik… - Nature Reviews …, 2019 - nature.com
Narcolepsy is the most common neurological cause of chronic sleepiness. The discovery
about 20 years ago that narcolepsy is caused by selective loss of the neurons producing …
about 20 years ago that narcolepsy is caused by selective loss of the neurons producing …
[HTML][HTML] Diagnosis of central disorders of hypersomnolence: a reappraisal by European experts
GJ Lammers, CLA Bassetti, L Dolenc-Groselj… - Sleep medicine …, 2020 - Elsevier
The aim of this European initiative is to facilitate a structured discussion to improve the next
edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter …
edition of the International Classification of Sleep Disorders (ICSD), particularly the chapter …