The treatment of peripheral nerve defects has always been one of the most challenging
clinical practices in neurosurgery. Currently, nerve autograft is the preferred treatment …

During nervous system development, an extracellular matrix (ECM) plays a pivotal role
through surface topography and microenvironment signals in neurons and neurites …

Methods in nerve tissue engineering for peripheral nerve regeneration have recently
focused on the application of rapid three-dimensional (3D) printing with resorbable and …

Unlike other tissue types, the nervous tissue extends to a wide and complex environment
that provides a plurality of different biochemical and topological stimuli, which in turn defines …

The human nervous system is a remarkably complex physiological network that is inherently
challenging to study because of obstacles to acquiring primary samples. Animal models …

Nerve guidance conduits (NGCs) have been drawing considerable attention as an aid to
promote regeneration of injured axons across damaged peripheral nerves. Ideally, NGCs …

Neural regeneration devices interface with the nervous system and can provide flexibility in
material choice, implantation without the need for additional surgeries, and the ability to …

Biofabrication techniques have endeavored to improve the regeneration of the peripheral
nervous system (PNS), but nothing has surpassed the performance of current clinical …

After many decades of biomaterials research for peripheral nerve regeneration, a clinical
product (the nerve guide), is emerging as a proven alternative for relatively short injury gaps …

Over the past two decades, a number of fabrication methods, including 3D printing and
bioprinting, have emerged as promising technologies to bioengineer nerve conduits that …