Benzodiazepines revisited—will we ever learn?
M Lader - Addiction, 2011 - Wiley Online Library
Aims To re‐examine various aspects of the benzodiazepines (BZDs), widely prescribed for
50 years, mainly to treat anxiety and insomnia. It is a descriptive review based on the Okey …
50 years, mainly to treat anxiety and insomnia. It is a descriptive review based on the Okey …
Benzodiazepine use and risk of dementia in the elderly population: a systematic review and meta-analysis
Background: Benzodiazepines are a widely used medication in developed countries,
particularly among elderly patients. However, benzodiazepines are known to affect memory …
particularly among elderly patients. However, benzodiazepines are known to affect memory …
[PDF][PDF] Benzodiazepine use and risk of Alzheimer's disease: case-control study
SB De Gage, Y Moride, T Ducruet, T Kurth, H Verdoux… - Bmj, 2014 - bmj.com
Objectives To investigate the relation between the risk of Alzheimer's disease and exposure
to benzodiazepines started at least five years before, considering both the dose-response …
to benzodiazepines started at least five years before, considering both the dose-response …
Benzodiazepine use and risk of dementia: prospective population based study
SB de Gage, B Bégaud, F Bazin, H Verdoux… - Bmj, 2012 - bmj.com
Objective To evaluate the association between use of benzodiazepines and incident
dementia. Design Prospective, population based study. Setting PAQUID study, France …
dementia. Design Prospective, population based study. Setting PAQUID study, France …
Benzodiazepine use and risk of incident dementia or cognitive decline: prospective population based study
SL Gray, S Dublin, O Yu, R Walker, M Anderson… - bmj, 2016 - bmj.com
Objective To determine whether higher cumulative use of benzodiazepines is associated
with a higher risk of dementia or more rapid cognitive decline. Design Prospective …
with a higher risk of dementia or more rapid cognitive decline. Design Prospective …
Psychological burden of PTSD, depression, and their comorbidity in the US veteran population: Suicidality, functioning, and service utilization
Background Emerging evidence suggests that comorbid posttraumatic stress disorder
(PTSD) and major depressive disorder (PTSD/MDD) may impose an even greater burden …
(PTSD) and major depressive disorder (PTSD/MDD) may impose an even greater burden …
Benzodiazepine harm: how can it be reduced?
M Lader - British journal of clinical pharmacology, 2014 - Wiley Online Library
The benzodiazepines (BZDs) are anxiolytics, hypnotics, anticonvulsants, muscle‐relaxants
and induce anaesthesia. Adverse effects comprise sedation subjectively and cognitive and …
and induce anaesthesia. Adverse effects comprise sedation subjectively and cognitive and …
[HTML][HTML] Neurocognitive effects of melatonin treatment in healthy adults and individuals with Alzheimer's disease and insomnia: a systematic review and meta-analysis …
DM Sumsuzzman, J Choi, Y Jin, Y Hong - Neuroscience & Biobehavioral …, 2021 - Elsevier
Endogenous melatonin levels are inversely associated with age and cognitive deficits.
Although melatonin can improve psychopathological behavior disturbances in clinical trials …
Although melatonin can improve psychopathological behavior disturbances in clinical trials …
Benzodiazepine use and cognitive decline in the elderly
JD Picton, AB Marino, KL Nealy - The Bulletin of the American …, 2018 - academic.oup.com
Purpose Published evidence on the relationship between benzodiazepine exposure and
altered cognition in the geriatric population is reviewed. Summary Benzodiazepines …
altered cognition in the geriatric population is reviewed. Summary Benzodiazepines …
Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression
BACKGROUND: Adult neurogenesis is coupled to angiogenesis in neurogenic niches in the
dentate gyrus (DG) and increased by antidepressants in rodents. We hypothesized that, in …
dentate gyrus (DG) and increased by antidepressants in rodents. We hypothesized that, in …