The history of dementia is probably as old as mankind itself. In recent years, considerable
advances have been made in our understanding of the epidemiology, the pathogenesis and …

Folate is necessary for DNA and mtDNA integrity and via folate/B12-dependent methionine
cycle for methylation of multiple substrates (epigenetic DNA and enzymes) and methylation …

A Korean version of the Consortium to Establish a Registry for Alzheimer's Disease
Assessment Packet (CERAD-K) was created. The English-American version of CERAD …

Age-related dementia and cognitive decline are substantial public health problems that are
projected to increase in the first half of this century as the proportion of older persons in the …

Little is known about the relative benefits of cognitively stimulating activities at different
points in the lifespan. In a cohort of 576 older persons without dementia, we assessed …

Structural and functional magnetic resonance imaging (fMRI) was performed on 21 healthy
elderly controls, 14 subjects with mild cognitive impairment (MCI) and 15 patients with mild …

Abstract Introduction Autosomal-dominant Alzheimer's disease (ADAD) represents a crucial
population for identifying prevention strategies that might modify disease course for …

The objective of the study was to examine variability across multiple prospective cohort
studies in level and rate of cognitive decline by race/ethnicity and years of education. We …

Objective. To compare the validity of different instruments for screening and diagnosis of
dementia and to provide threshold scores for these purposes, ie screening focusing on a …

Background: Falling victim to financial scams can have a significant impact upon social and
financial wellbeing and independence. A large proportion of scam victims are older adults …