Cheminformatics-based identification of potential novel anti-SARS-CoV-2 natural compounds of African origin

SK Kwofie, E Broni, SO Asiedu, GB Kwarko, B Dankwa… - Molecules, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome virus 2 (SARS-CoV-2) has impacted negatively on public health and …

In vitro anticancer screening and preliminary mechanistic study of A-ring substituted Anthraquinone derivatives

I Morgan, LA Wessjohann, GN Kaluđerović - Cells, 2022 - mdpi.com
Anthraquinone derivatives exhibit various biological activities, eg, antifungal, antibacterial
and in vitro antiviral activities. They are naturally produced in many fungal and plant families …

Thiophene-2-carboxamide derivatives of anthraquinone: A new potent antitumor chemotype

YL Volodina, AS Tikhomirov, LG Dezhenkova… - European Journal of …, 2021 - Elsevier
The anthraquinone scaffold has long been known as a source of efficacious antitumor drugs.
In particular, the various chemical modifications of the side chains in this scaffold have …

Synthesis, crystal structures and anticancer studies of morpholinyldithiocarbamato Cu (II) and Zn (II) complexes

PA Ajibade, FP Andrew, NL Botha, N Solomane - Molecules, 2020 - mdpi.com
Cu (II) and Zn (II) morpholinyldithiocarbamato complexes, formulated as [Cu (MphDTC) 2]
and [Zn (μ-MphDTC) 2 (MphDTC) 2], where MphDTC is morpholinyldithiocarbamate were …

Design, synthesis and bioactive properties of a class of macrocycles with tunable functional groups and ring size

L Thurakkal, P Nanjan, M Porel - Scientific Reports, 2022 - nature.com
The design and synthesis of a versatile class of macrocycles with tunable functional groups
and ring size are unfolded. Herein, a synthetic strategy is reported to furnish a new class of …

Efficient mercury removal in 30 seconds by designing a dithiocarbamate-based organic polymer with customizable functionalities and tunable properties

L Thurakkal, M Porel - Environmental Science: Water Research & …, 2023 - pubs.rsc.org
A novel class of organic polymer (OP) with customizable functional groups in the backbone
and side-chain was designed and synthesized to remove toxic Hg2+ ions from contaminated …

Spectral, quantum chemical, biological activity, and molecular docking analysis of 1, 8-dihydroxyanthraquinone: A target drug exploration

A Garg, BS Yadav - Materials Today: Proceedings, 2023 - Elsevier
In this current effort, the 1 H and 13 C NMR spectra as well as quantum chemical
computational effort of 1, 8 DHAQ molecule analyzed based on density functional theory …

[PDF][PDF] Comparative Anticonvulsant Activity of Leaf, Stem Bark and Root Bark Extracts of Bombax costatum Pellegr. and Vuillet in Acute Models of Epilepsy: doi. org …

AB Nazifi, A Ahmed, FI Hassan… - Tropical Journal of …, 2020 - researchgate.net
Bombax costatum is a tropical medicinal plant utilized conventionally for the treatment of
epilepsy. The parts used are leaves, stem and roots. Nevertheless, there is paucity of …

[PDF][PDF] Synthesis and study of antimicrobial activity of 2-dithiocarbamate-N-(9, 10-dioxo-9, 10-dihydroanthracenyl) acetamides

V Zvarych, M Stasevych… - … Research in Applied …, 2021 - biointerfaceresearch.com
The global emergence and dissemination of multidrug-resistant fungal and bacterial
pathogens is a serious public health threat. The development of novel highly active …

[PDF][PDF] N-(9, 10-Dioxo-9, 10-dihydroanthracen-1 (2)-yl)-2-(R-thio) Acetamides: Synthesis, Antioxidant and Antiplatelet Activity.

M Stasevych, V Zvarych, O Yaremkevych… - Acta Chimica …, 2022 - researchgate.net
The synthesis of new N-(9, 10-dioxo-9, 10-dihydroanthracen-1 (2)-yl)-2-(R-thio) acetamides
was carried out using reaction of 2-chloro-N-(9, 10-dioxo-9, 10-dihydroanthracene-1 (2)-yl) …