Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …

Metabolic adaptation to viral infections critically determines the course and manifestations of
disease. At the systemic level, a significant feature of viral infection and inflammation that …

The NLRP3 inflammasome is linked to sterile and pathogen-dependent inflammation, and
its dysregulation underlies many chronic diseases. Mitochondria have been implicated as …

Heightened inflammatory response is a prominent feature of severe COVID-19 disease. We
report that the SARS-CoV-2 ORF3a viroporin activates the NLRP3 inflammasome, the most …

Cadmium (Cd), a toxic heavy metal pollutant, is a threat to human and eatable fish health.
Common carps are widely cultivated and eaten by humans. However, there are no reports …

Metformin is the oldest and most commonly used first-line antidiabetic drug because of its
good clinical efficacy, high safety, low cost and easy access. At the same time, in recent …

Association of diabetes with an elevated risk of cardiac failure has been clinically evident.
Diabetes potentiates diastolic and systolic cardiac failure following the myocardial infarction …

Diabetic cardiomyopathy (DCM) is a chronic complication of diabetes mellitus, characterized
by abnormalities of myocardial structure and function. Researches on the models of type 1 …

The NLR family pyrin domain containing 3 (NLRP3) inflammasome is responsible for the
sensation of various pathogenic and non-pathogenic damage signals and has a vital role in …

Metformin is the first-line option for treating newly diagnosed diabetic patients and also
involved in other pharmacological actions, including antitumor effect, anti-aging effect …