Ergosterol is an essential component of fungal cell membranes that determines the fluidity,
permeability and activity of membrane-associated proteins. Ergosterol biosynthesis is a …

During brewery handling, production strains of yeast must respond to fluctuations in
dissolved oxygen concentration, pH, osmolarity, ethanol concentration, nutrient supply and …

Eukaryotic cells respond to low-oxygen concentrations by upregulating hypoxic nuclear
genes (hypoxic signaling). Although it has been shown previously that the mitochondrial …

High-throughput technology has facilitated genome-scale analyses of transcriptomic
adjustments in response to environmental perturbations with an oxygen deprivation …

Most genes change expression levels across conditions, but it is unclear which of these
changes represents specific regulation and what determines their quantitative degree. Here …

Saccharomyces cerevisiae is an important platform organism for synthesis of chemicals and
fuels. However, the promoters used in most pathway engineering studies in S. cerevisiae …

Addition of glucose to yeast cells increases their growth rate and results in a massive
restructuring of their transcriptional output. We have used microarray analysis in conjunction …

Significant insight about biological networks arises from the study of network motifs—overly
abundant network subgraphs,—but such wiring patterns do not specify when and how …

Fission yeast sterol regulatory element binding protein (SREBP), called Sre1p, functions in
an oxygen-sensing pathway to allow adaptation to fluctuating oxygen concentrations. The …

Budding yeast Saccharomyces cerevisiae survives in microenvironments utilizing networks
of regulators and ATP‐binding cassette (ABC) transporters to circumvent toxins and a variety …