Stability of chitosan—a challenge for pharmaceutical and biomedical applications

E Szymańska, K Winnicka - Marine drugs, 2015 - mdpi.com
Chitosan—one of the natural multifunctional polymers—due to its unique and versatile
biological properties is regarded as a useful compound in medical and pharmaceutical …

Progress and prospects of polysaccharide-based nanocarriers for oral delivery of proteins/peptides

H Yuan, C Guo, L Liu, L Zhao, Y Zhang, T Yin… - Carbohydrate …, 2023 - Elsevier
The oral route has long been recognized as the most preferred route for drug delivery as it
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …

Concepts for developing physical gels of chitosan and of chitosan derivatives

P Sacco, F Furlani, G De Marzo, E Marsich, S Paoletti… - Gels, 2018 - mdpi.com
Chitosan macro-and micro/nano-gels have gained increasing attention in recent years,
especially in the biomedical field, given the well-documented low toxicity, degradability, and …

Colloidal polyelectrolyte complexes from hyaluronic acid: Preparation and biomedical applications

HV Le, D Le Cerf - Small, 2022 - Wiley Online Library
Hyaluronic acid (HA) is a naturally occurring polysaccharide which has been extensively
exploited in biomedical fields owing to its outstanding biocompatibility. Self‐assembly of HA …

Characterization of self-assembled polyelectrolyte complex nanoparticles formed from chitosan and pectin

NP Birch, JD Schiffman - Langmuir, 2014 - ACS Publications
Chronic wounds continue to be a global healthcare concern. Thus, the development of new
nanoparticle-based therapies that treat multiple symptoms of these “non-healing” wounds …

Polymeric nanoparticles for increasing oral bioavailability of curcumin

A Umerska, C Gaucher, F Oyarzun-Ampuero… - Antioxidants, 2018 - mdpi.com
Despite the promising biological and antioxidant properties of curcumin, its medical
applications are limited due to poor solubility in water and low bioavailability. Polymeric …

The role of mucin in the toxicological impact of polystyrene nanoparticles

I Inkielewicz-Stepniak, L Tajber, G Behan, H Zhang… - Materials, 2018 - mdpi.com
The development of novel oral drug delivery systems is an expanding area of research and
both new approaches for improving their efficacy and the investigation of their potential …

[HTML][HTML] Hyaluronic acid nanoparticles as nanomedicine for treatment of inflammatory diseases

NV Rao, JG Rho, W Um, PK Ek, VQ Nguyen, BH Oh… - Pharmaceutics, 2020 - mdpi.com
Owing to their unique biological functions, hyaluronic acid (HA) and its derivatives have
been explored extensively for biomedical applications such as tissue engineering, drug …

Stabilization of chitosan/hyaluronan colloidal polyelectrolyte complexes in physiological conditions

D Wu, T Delair - Carbohydrate polymers, 2015 - Elsevier
Polyelectrolyte complexes (PECs) between hyaluronan (HYA) and chitosan were obtained
by the one-shot addition of default amounts of polyanion to an excess of polycation. The …

Hyaluronan/colistin polyelectrolyte complexes: Promising antiinfective drug delivery systems

NV Dubashynskaya, SV Raik, YA Dubrovskii… - International Journal of …, 2021 - Elsevier
Nanotechnology-based modification of known antimicrobial agents is a rational and
straightforward way to improve their safety and effectiveness. The aim of this study was to …