Cystic fibrosis transmembrane conductance regulator (CFTR) functions as a channel that
regulates the transport of ions and the movement of water across the epithelial barrier …

Chronic inflammation, oxidative stress, mucus plugging, airway remodeling, and respiratory
infections are the hallmarks of the cystic fibrosis (CF) lung disease. The airway epithelium is …

In this study we analyzed the microRNA profile of cystic fibrosis (CF) bronchial epithelial IB3–
1 cells infected with Pseudomonas aeruginosa by microarray and quantitative RT-PCR …

The most relevant cause of morbidity and mortality in cystic fibrosis (CF) patients is the lung
pathology characterized by chronic infection and inflammation sustained mainly by …

Lung disease is the major cause of morbidity and mortality of cystic fibrosis (CF), an
autosomal recessive disease caused by mutations in CF transmembrane-conductance …

Multiple evidences indicate that inflammation is an event occurring prior to infection in
patients with cystic fibrosis. The self-perpetuating inflammatory cycle may play a pathogenic …

With knowledge of the molecular behaviour of the cystic fibrosis transmembrane
conductance regulator (CFTR), its physiological role and dysfunction in cystic fibrosis (CF) …

Despite increased morbidity associated with secondary respiratory viral infections in cystic
fibrosis (CF) patients with chronic Pseudomonas aeruginosa infection, the underlying …

The emergence of phage-resistant mutants is a key aspect of lytic phages-bacteria
interaction and the main driver for the co-evolution between both organisms. Here, we …

Background Mutation of the cystic fibrosis transmembrane-conductance regulator (CFTR)
causes cystic fibrosis (CF) but not all CF aspects can easily be explained by deficient ion …