The role of epigenetic modifications in drug resistance and treatment of breast cancer

M Karami Fath, A Azargoonjahromi, A Kiani… - Cellular & Molecular …, 2022 - Springer
Background Breast cancer is defined as a biological and molecular heterogeneous disorder
that originates from breast cells. Genetic predisposition is the most important factor giving …

MicroRNAs in breast cancer: Roles, functions, and mechanism of actions

M Abolghasemi, SS Tehrani, T Yousefi… - Journal of cellular …, 2020 - Wiley Online Library
Breast cancer is one of the most lethal malignancies in women in the world. Various factors
are involved in the development and promotion of the malignancy; most of them involve …

Delivery of miR-200c-3p using tumor-targeted mesoporous silica nanoparticles for breast cancer therapy

I Garrido-Cano, A Adam-Artigues… - … Applied Materials & …, 2023 - ACS Publications
Despite advances in breast cancer treatment, it remains the leading cause of cancer-related
death in women worldwide. In this context, microRNAs have emerged as potential …

miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance

M Mutlu, U Raza, Ö Saatci, E Eyüpoğlu… - Journal of Molecular …, 2016 - Springer
Abstract MicroRNAs (miRNAs) are 20–22-nucleotide small endogenous non-coding RNAs
which regulate gene expression at post-transcriptional level. In the last two decades …

MiR-200 family and cancer: From a meta-analysis view

GL Huang, J Sun, Y Lu, Y Liu, H Cao, H Zhang… - Molecular Aspects of …, 2019 - Elsevier
The role of microRNAs (miRNAs) in cancer development was implicated as oncogene or
tumor suppressor. One of the miRNA family, the miR-200 family, was mainly characterized …

Identification of MicroRNAs as breast cancer prognosis markers through the cancer genome atlas

JTH Chang, F Wang, W Chapin, RS Huang - PloS one, 2016 - journals.plos.org
Breast cancer is the second-most common cancer and second-leading cause of cancer
mortality in American women. The dysregulation of microRNAs (miRNAs) plays a key role in …

The effects of mutant Ras proteins on the cell signalome

T Takács, G Kudlik, A Kurilla, B Szeder, L Buday… - Cancer and Metastasis …, 2020 - Springer
The genetic alterations in cancer cells are tightly linked to signaling pathway dysregulation.
Ras is a key molecule that controls several tumorigenesis-related processes, and mutations …

The role of miR-200 family in the regulation of hallmarks of cancer

K Klicka, TM Grzywa, A Mielniczuk, A Klinke… - Frontiers in …, 2022 - frontiersin.org
MiRNAs are short non-coding RNAs that regulate gene expression post-transcriptionally
contributing to the development of different diseases including cancer. The miR-200 family …

Involvement of microRNA modifications in anticancer effects of major polyphenols from green tea, coffee, wine, and curry

T Ohishi, S Hayakawa, N Miyoshi - Critical Reviews in Food …, 2023 - Taylor & Francis
Epidemiological studies have shown that consumption of green tea, coffee, wine, and curry
may contribute to a reduced risk of various cancers. However, there are some cancer site …

Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer

C Papadaki, M Stratigos, G Markakis, M Spiliotaki… - Breast Cancer …, 2018 - Springer
Background In primary breast cancer metastases frequently arise from a state of dormancy
that may persist for extended periods of time. We investigated the efficacy of plasma micro …