DNA-encoded chemical libraries (DELs) represent a versatile and powerful technology
platform for the discovery of small-molecule ligands to protein targets of biological and …

Click chemistry, proposed nearly 20 years ago, promised access to novel chemical space by
empowering combinatorial library synthesis with a “few good reactions”. These click …

Over the past decade, DNA-encoded libraries (DELs) have emerged as a leading platform
for small molecule drug discovery among pharmaceutical companies, biotech companies …

In recent years, DNA-encoded chemical libraries (DECLs) have attracted considerable
attention as a potential discovery tool in drug development. Screening encoded libraries …

DNA-encoded library technology (DELT) was introduced to our medicinal chemistry society
more than 20 years ago. The application of DELT in the development of clinical candidates …

The discovery of organic ligands that bind specifically to proteins is a central problem in
chemistry, biology, and the biomedical sciences. The encoding of individual organic …

DNA Encoded Libraries have proven immensely powerful tools for lead identification. The
ability to screen billions of compounds at once has spurred increasing interest in DEL …

The world is totally dependent on medications. As science progresses, new, better, and
cheaper drugs are needed more than ever. The pharmaceutical industry has been …

DNA-encoded libraries (DEL)-based discovery platforms have recently been widely adopted
in the pharmaceutical industry, mainly due to their powerful diversity and incredible number …

Conspectus DNA-encoded chemical libraries (DECLs) represent a promising tool in drug
discovery. DECL technology allows the synthesis and screening of chemical libraries of …