The endoplasmic reticulum (ER) is a cellular organelle important for regulating calcium
homeostasis, lipid metabolism, protein synthesis, and posttranslational modification and …

Among various factors, such as an unhealthy diet or a sedentarity lifestyle, excessive
fructose consumption is known to favor nonalcoholic fatty liver disease (NAFLD), as fructose …

Obesity has been described as a global epidemic and is a low-grade chronic inflammatory
disease that arises as a consequence of energy imbalance. Obesity increases the risk of …

Sarcopenia frequently occurs with aging and leads to major adverse impacts on activities of
daily living and quality of life in elderly individuals. Omega-3 polyunsaturated fatty acid …

The endoplasmic reticulum (ER) stress response, also commonly known as the unfolded
protein response (UPR), is an adaptive response used to align ER functional capacity with …

The endoplasmic reticulum (ER) is a critical site of protein, lipid, and glucose metabolism,
lipoprotein secretion, and calcium homeostasis. Many of the sensing, metabolizing, and …

Dyslipidemia is a common nutritional and metabolic disorder in patients with chronic kidney
disease. Accumulating evidence supports the hypothesis that prolonged metabolic …

Ceramide accumulation is a hallmark in the manifestation of numerous obesity-related
diseases, such as type 2 diabetes mellitus and atherosclerosis. Until the early 2000s …

Very few sports use only endurance or strength. Outside of running long distances on a flat
surface and power-lifting, practically all sports require some combination of endurance and …

Insulin resistance is a major characteristic of obesity and type 2 diabetes (T2DM). During the
last decade, endoplasmic reticulum (ER) stress has emerged as a new player in this field …