Testicular cancer is a curable cancer. The success of physicians in curing the disease is
underpinned by multidisciplinary advances. Cisplatin-based combination chemotherapy and …

The outcome of metastatic testicular germ cell tumor patients has been dramatically
improved by cisplatin-based chemotherapy combinations. However, up to 30% of patients …

Background: We evaluated systemic immune-inflammation index (SII) and its association
with patient outcome in germ-cell tumours (GCTs). Methods: Two independent cohorts of …

Germ cell tumors (GCTs) represent a heterogeneous neoplasm family affecting gonads and
rarely occurring in extragonadal areas. Most of patients have a good prognosis, often even …

Introduction. Chronic inflammatory response is one of major contributors in the development
of hepatocellular carcinoma (HCC). Inflammatory molecules, such as cytokines and growth …

Testicular germ cell tumors are unique among solid cancers. Historically, this disease was
deadly if progressed beyond the stage I. The implementation of cisplatin-based …

Background Testicular germ cell tumours (GCT s) are the only universally curable solid
malignancy. The long‐term cure rate of> 95% is attributed to the extraordinary sensitivity to …

Germ cell tumors are the most common malignant tumors in male young adults. Platinum-
based chemotherapy has dramatically improved the outcome of metastatic germ cell tumor …

Testicular germ cell tumors (TGCTs) represent the most common neoplasia among young
men. Management of TGCTs is an excellent example of curative outcomes in clinical …

Background WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic
development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) …