Induced pluripotent stem cells as a tool for modeling hematologic disorders and as a potential source for cell-based therapies

P Pratumkaew, S Issaragrisil, S Luanpitpong - Cells, 2021 - mdpi.com
The breakthrough in human induced pluripotent stem cells (hiPSCs) has revolutionized the
field of biomedical and pharmaceutical research and opened up vast opportunities for drug …

Optimized and Scalable Precoating‐Free Reprogramming of Human Peripheral Blood Mononuclear Cells into iPSCs

E Fiacco, S Landi, J Zasso, C Ambrosini… - Current …, 2024 - Wiley Online Library
Human disease modeling has been profoundly transformed by the introduction of human
induced pluripotent stem cells (iPSCs), marking the onset of a new era. This ground …

An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming

M Weng, H Hu, MS Graus, DS Tan, Y Gao, S Ren… - Science …, 2023 - science.org
Advanced strategies to interconvert cell types provide promising avenues to model cellular
pathologies and to develop therapies for neurological disorders. Yet, methods to directly …

Strategies for iPSC expansion: from feeder cells to laminin

FCP Mesquita, C Hochman-Mendez… - Recent Advances in iPSC …, 2021 - Elsevier
Establishment of expansion systems that are synthetic, defined, and stable will help
accelerate the translation of human pluripotent stem cells (hPSCs). This chapter describes …