Applications of western blot technique: From bench to bedside
GH Meftahi, Z Bahari… - Biochemistry and …, 2021 - Wiley Online Library
Western blot (WB) or immunoblot is a workhorse method. It is commonly used by biologists
for study of different aspects of protein biomolecules. In addition, it has been widely used in …
for study of different aspects of protein biomolecules. In addition, it has been widely used in …
Progress on phage display technology: tailoring antibodies for cancer immunotherapy
RKA França, IC Studart, MRL Bezerra, LQ Pontes… - Viruses, 2023 - mdpi.com
The search for innovative anti-cancer drugs remains a challenge. Over the past three
decades, antibodies have emerged as an essential asset in successful cancer therapy. The …
decades, antibodies have emerged as an essential asset in successful cancer therapy. The …
Applications of the phage display technology in molecular biology, biotechnology and medicine
K Pierzynowska, J Morcinek-Orłowska… - Critical Reviews in …, 2023 - Taylor & Francis
The phage display technology is based on the presentation of peptide sequences on the
surface of virions of bacteriophages. Its development led to creation of sophisticated systems …
surface of virions of bacteriophages. Its development led to creation of sophisticated systems …
Human antibodies neutralizing diphtheria toxin in vitro and in vivo
EV Wenzel, M Bosnak, R Tierney, M Schubert… - Scientific reports, 2020 - nature.com
Diphtheria is an infectious disease caused by Corynebacterium diphtheriae. The bacterium
primarily infects the throat and upper airways and the produced diphtheria toxin (DT), which …
primarily infects the throat and upper airways and the produced diphtheria toxin (DT), which …
Phage-displayed peptides for targeting tyrosine kinase membrane receptors in cancer therapy
Receptor tyrosine kinases (RTKs) regulate critical physiological processes, such as cell
growth, survival, motility, and metabolism. Abnormal activation of RTKs and relative …
growth, survival, motility, and metabolism. Abnormal activation of RTKs and relative …
A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the cyclin D1–CDK4 interaction
J Zhao, Y Wu, T Xiao, C Cheng, T Zhang, Z Gao… - Breast Cancer Research …, 2023 - Springer
Background Cyclin D1 overexpression may contribute to development of various cancers,
including breast cancer, and thus may serve as a key cancer diagnostic marker and …
including breast cancer, and thus may serve as a key cancer diagnostic marker and …
Pyruvate dehydrogenase complex—enzyme 2, a new target for Listeria spp. detection identified using combined phage display technologies
GMSG Moreira, SMS Köllner, S Helmsing, L Jänsch… - Scientific Reports, 2020 - nature.com
The genus Listeria comprises ubiquitous bacteria, commonly present in foods and food
production facilities. In this study, three different phage display technologies were employed …
production facilities. In this study, three different phage display technologies were employed …
Understanding and modulating antibody fine specificity: lessons from combinatorial biology
G Rojas - Antibodies, 2022 - mdpi.com
Combinatorial biology methods such as phage and yeast display, suitable for the generation
and screening of huge numbers of protein fragments and mutated variants, have been …
and screening of huge numbers of protein fragments and mutated variants, have been …
Whole-Cell Display of Phosphotransferase in Escherichia coli for High-Efficiency Extracellular ATP Production
S Zhao, G Yang, X Xie, G Yan, F Wang, W Chen, L Ma - Biomolecules, 2022 - mdpi.com
Adenosine triphosphate (ATP), as a universal energy currency, takes a central role in many
biochemical reactions with potential for the synthesis of numerous high-value products …
biochemical reactions with potential for the synthesis of numerous high-value products …
Identification of Heterophilic Epitopes of H1N1 Influenza Virus Hemagglutinin
J Sun, C Guo, G Wang, L Yan, Q Feng, Y Li, X Huo… - Current …, 2023 - Springer
Our previous studies found that the H1-50 monoclonal antibody (mAb) of influenza A virus
hemagglutinin (HA) cross-reacted with pancreatic tissue and islet β-cells, and further studies …
hemagglutinin (HA) cross-reacted with pancreatic tissue and islet β-cells, and further studies …