A second space age spanning omics, platforms and medicine across orbits
The recent acceleration of commercial, private and multi-national spaceflight has created an
unprecedented level of activity in low Earth orbit, concomitant with the largest-ever number …
unprecedented level of activity in low Earth orbit, concomitant with the largest-ever number …
Biomonitoring and precision health in deep space supported by artificial intelligence
Human exploration of deep space will involve missions of substantial distance and duration.
To effectively mitigate health hazards, paradigm shifts in astronaut health systems are …
To effectively mitigate health hazards, paradigm shifts in astronaut health systems are …
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight
Spaceflight induces an immune response in astronauts. To better characterize this effect, we
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses
myriad biomedical challenges to the human body, which are becoming increasingly relevant …
myriad biomedical challenges to the human body, which are becoming increasingly relevant …
Hemolysis contributes to anemia during long-duration space flight
G Trudel, N Shahin, T Ramsay, O Laneuville… - Nature medicine, 2022 - nature.com
Anemia in astronauts has been noted since the first space missions, but the mechanisms
contributing to anemia in space flight have remained unclear. Here, we show that space …
contributing to anemia in space flight have remained unclear. Here, we show that space …
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight
Spaceflight can change metabolic, immunological, and biological homeostasis and cause
skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact …
skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact …
Noise-boosted weak signal detection in fractional nonlinear systems enhanced by increasing potential-well width and its application to mechanical fault diagnosis
Z Qiao, Y He, C Liao, R Zhu - Chaos, Solitons & Fractals, 2023 - Elsevier
Noise is seen as the annoying something for weak signal detection, but noise is beneficial to
enhance weak signals of interest embedded in noise in nonlinear systems. Moreover, the …
enhance weak signals of interest embedded in noise in nonlinear systems. Moreover, the …
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA)
Abstract The SpaceX Inspiration4 mission provided a unique opportunity to study the impact
of spaceflight on the human body. Biospecimen samples were collected from four crew …
of spaceflight on the human body. Biospecimen samples were collected from four crew …
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
As spaceflight becomes more common with commercial crews, blood-based measures of
crew health can guide both astronaut biomedicine and countermeasures. By profiling …
crew health can guide both astronaut biomedicine and countermeasures. By profiling …
Biological research and self-driving labs in deep space supported by artificial intelligence
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …
organisms, develop foundational knowledge to support deep space exploration and …