DNA is the source of genetic information, and preserving its integrity is essential in order to
sustain life. The genome is continuously threatened by different types of DNA lesions, such …

Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …

During CRISPR-directed gene editing, multiple gene repair mechanisms interact to produce
a wide and largely unpredictable variety of sequence changes across an edited population …

The fidelity of genetic information is essential for cellular function and viability. DNA double-
strand breaks (DSBs) pose a significant threat to genome integrity, necessitating efficient …

Homology-directed repair (HDR) of a DNA break allows copying of genetic material from an
exogenous DNA template and is frequently exploited in CRISPR-Cas9 genome editing …

As the possibilities of CRISPR-Cas9 technology have been revealed, we have entered a
new era of research aimed at increasing its specificity and safety. This stage of technology …

X-ray nanoscintillator-based photoresponsive therapy is emerging as a promising strategy to
treat in vivo tumors, necessitating the development of nanoscintillators with X-ray-excited …

Mutational outcomes following CRISPR-Cas9-nuclease cutting in mammalian cells have
recently been shown to be predictable and, in certain cases, skewed toward single …

Potato (Solanum tuberosum) is a highly diverse tetraploid crop. Elite cultivars are extremely
heterozygous with a high prevalence of small length polymorphisms (indels) and single …

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, continues to spread around the world with serious cases and deaths. It has also …