Deciphering the secret of successful aging depends on understanding the patterns and
biological underpinnings of cognitive and behavioral changes throughout adulthood. That …

Magnetic resonance (MR) spectroscopy is an analytical method used in chemistry that
enables the identification and quantification of metabolites in samples. It differs from …

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain.
Although measurements of GABA levels in vivo in the human brain using edited proton …

The regional distribution of brain metabolites was studied in several cortical white and gray
matter areas, cerebellum, and thalamus of young adults with use of quantitative single‐voxel …

N-Acetyl aspartate (NAA) is the second most abundant amino acid in the human brain. NAA
is synthesized by l-aspartate N-acetyl transferase or by cleavage from N-acetyl aspartyl …

Longitudinal and transverse relaxation times were measured for proton MRS signals from
human brain metabolites at 3 T using a short‐echo STEAM protocol and a surface coil as a …

Purpose To measure 1H relaxation times of cerebral metabolites at 3 T and to investigate
regional variations within the brain. Materials and Methods Investigations were performed …

Despite the importance of monitoring and correlating neurotransmitter concentrations in the
brain with observable behavior and brain areas in which they act, in vivo measurement of …

In vivo longitudinal relaxation times of N‐acetyl compounds (NA), choline‐containing
substances (Cho), creatine (Cr), myo‐inositol (mI), and tissue water were measured at 1.5 …

Volumetric proton magnetic resonance spectroscopic imaging (MRSI) was used to generate
brain metabolite maps in 15 young and 19 elderly adult volunteers. All subjects also had …