Perineural invasion in pancreatic ductal adenocarcinoma: from molecules towards drugs of clinical relevance

F Selvaggi, E Melchiorre, I Casari, S Cinalli, M Cinalli… - Cancers, 2022 - mdpi.com
Simple Summary A few types of cancers are currently as challenging and difficult to defeat
as pancreatic ductal adenocarcinoma. Several reasons contribute to the complexity of this …

[HTML][HTML] Novel therapeutical approaches based on neurobiological and genetic strategies for diabetic polyneuropathy–A review

EK Sher, A Džidić-Krivić, A Karahmet… - Diabetes & Metabolic …, 2023 - Elsevier
Background Neuropathy is among the most often reported consequences of diabetes and
the biggest cause of morbidity and mortality in people suffering from this life-long disease …

Preparation, pungency, and bioactivity of capsaicin: a review

Q Zhang, S Huang, OP Soladoye… - International Journal of …, 2024 - academic.oup.com
Capsaicin is the main pungent compound in red pepper responsible for its dual attributes of
culinary utility and bioactive efficacy. This review aims to systematically review the …

Novel drug targets and emerging pharmacotherapies in neuropathic pain

J Bernatoniene, A Sciupokas, DM Kopustinskiene… - Pharmaceutics, 2023 - mdpi.com
Neuropathic pain is a debilitating condition characterized by abnormal signaling within the
nervous system, resulting in persistent and often intense sensations of pain. It can arise from …

Pain in the context of sensory deafferentation

SP Cohen, MJ Caterina, SY Yang… - …, 2024 - ingentaconnect.com
Pain that accompanies deafferentation is one of the most mysterious and misunderstood
medical conditions. Prevalence rates for the assorted conditions vary considerably but the …

Mechanisms and therapeutic prospects of microglia-astrocyte interactions in neuropathic pain following spinal cord injury

Y Liu, X Cai, B Shi, Y Mo, J Zhang, W Luo, B Yu… - Molecular …, 2024 - Springer
Neuropathic pain is a prevalent and debilitating condition experienced by the majority of
individuals with spinal cord injury (SCI). The complex pathophysiology of neuropathic pain …

A Silver Lining of Neuropathic Pain: Predicting Favorable Functional Outcome in Spinal Cord Injury

ML Xu, XB Wu, Y Liang, N Li, X Hu, XD Lin… - Journal of Pain …, 2023 - Taylor & Francis
Background Neuropathic pain (NP) is a common and severe problem following spinal cord
injury (SCI). However, its relationship with functional outcome remains unclear. Methods A …

[PDF][PDF] Clinical Research & Reviews

EK Sher, A Dzidic-Krivic, A Karahmet… - Diabetes & Metabolic …, 2023 - researchgate.net
Background: Neuropathy is among the most often reported consequences of diabetes and
the biggest cause of morbidity and mortality in people suffering from this life-long disease …

High-dose capsaicin patch for pain relief: Clinical experience

Y Pepelyayeva, B Rardin, D Simpson… - TRP Channels as …, 2024 - Elsevier
This chapter provides an overview of the background, development, efficacy, safety
concerns, and practical considerations for the use of the high concentration capsaicin 8 …

[PDF][PDF] Novel Drug Targets and Emerging Pharmacotherapies in Neuropathic Pain. Pharmaceutics 2023, 15, 1799

J Bernatoniene, A Sciupokas, DM Kopustinskiene… - 2023 - academia.edu
Neuropathic pain is a debilitating condition characterized by abnormal signaling within the
nervous system, resulting in persistent and often intense sensations of pain. It can arise from …