Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer

KA Preethi, SC Selvakumar, K Ross, S Jayaraman… - Molecular Cancer, 2022 - Springer
Background Detecting cancer at an early stage before clinical manifestation could be an
effective strategy to decrease cancer mortality. Thus, identifying liquid biopsy biomarkers …

The role of exosomes in liquid biopsy for cancer diagnosis and prognosis prediction

S Li, M Yi, B Dong, X Tan, S Luo… - International journal of …, 2021 - Wiley Online Library
Liquid biopsy is a revolutionary strategy in cancer diagnosis and prognosis prediction, which
is used to analyze cancer cells or cancer‐derived products through biofluids such as blood …

Liquid biopsies, novel approaches and future directions

A Armakolas, M Kotsari, J Koskinas - Cancers, 2023 - mdpi.com
Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

Integrated approaches for precision oncology in colorectal cancer: The more you know, the better

P Andrei, P Battuello, G Grasso, E Rovera… - Seminars in cancer …, 2022 - Elsevier
Colorectal cancer (CRC) is one of the most common human malignancies accounting for
approximately 10% of worldwide cancer incidence and mortality. While early-stage CRC is …

Using all our genomes: Blood‐based liquid biopsies for the early detection of cancer

E Adams, GD Sepich‐Poore, S Miller‐Montgomery… - View, 2022 - Wiley Online Library
The pursuit of highly sensitive and specific cancer diagnostics based on cell‐free nucleic
acids isolated from minimally invasive liquid biopsies has been an area of intense research …

Circular RNA in colorectal cancer

T Li, WC Wang, V McAlister, Q Zhou… - Journal of cellular and …, 2021 - Wiley Online Library
Circular RNA (circRNA) is a highly abundant type of single‐stranded non‐coding RNA.
Novel research has discovered many roles of circRNA in colorectal cancer (CRC) including …

Extracellular vesicles as natural therapeutic agents and innate drug delivery systems for cancer treatment: Recent advances, current obstacles, and challenges for …

M Pirisinu, TC Pham, DX Zhang, TN Hong… - Seminars in Cancer …, 2022 - Elsevier
As cancer poses a significant threat to the well-being of humans on a global scale, many
researchers have embarked on the search for effective anticancer therapeutic agents. In …

miRNA-based potential biomarkers and new molecular insights in ulcerative colitis

J Zhou, J Liu, Y Gao, L Shen, S Li… - Frontiers in Pharmacology, 2021 - frontiersin.org
Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease, which usually
manifests as abdominal pain, diarrhea and hematochezia. The disease often recurs and is …

Circular RNA: A promising new star for the diagnosis and treatment of colorectal cancer

S Zhang, J Sun, M Gu, G Wang, X Wang - Cancer medicine, 2021 - Wiley Online Library
Background Colorectal cancer (CRC) is one of the most common malignant tumors of the
digestive tract. According to the research of circular RNAs in the CRC field, compared with …